anti-Rat (Rattus) Progesterone Receptor antibody for Immunoprecipitation

Recommended Progesterone Receptor Antibody (supplied by: Log in to see )

Antigen
Progesterone Receptor (PGR) Antibodies
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
611
103
96
25
11
11
9
6
6
5
4
4
2
1
1
1
1
1
1
1
Host
Mouse
329
292
3
1
Clonality
Monoclonal
Conjugate
This Progesterone Receptor antibody is un-conjugated
20
17
16
12
12
12
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
463
203
169
131
100
67
50
28
27
27
19
9
3
3
2
2
1
1
Supplier
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Catalog No. ABIN781813
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN266931 ICC IHC (fro) IF IHC (p) IP IHC WB Mouse IgG2a B form Log in to see Alpha PR6 0
1 ABIN625879 IF IHC IHC (p) IP WB Mouse IgG1, kappa Log in to see 0
1 ABIN1042662 IP WB Mouse IgG1 C-Term, AA 919-933 Log in to see C262 1
1 ABIN1042663 IP WB Mouse IgG1 C-Term, AA 919-933 Log in to see C262 1
1 ABIN341160 IP WB Mouse IgG1 AA 919-933 Log in to see C262 0
1 ABIN2471140 IF IP IHC WB Mouse IgG1 kappa Log in to see 0
1 ABIN1722411 IF IHC (p) IP WB Mouse IgG1 kappa Log in to see 0
1 ABIN209187 ICC IHC IHC (fro) IHC (p) IP WB Mouse IgG2a Log in to see 0
1 ABIN385236 IF IP WB Mouse IgG1, kappa Log in to see hPRa 7 0
1 ABIN2921639 IF/ICC IHC IP WB Rabbit AA 672-790 Log in to see Polyclonal 0

General

Antigen Progesterone Receptor (PGR) Antibodies
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(611), (103), (96), (25), (11), (11), (9), (6), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(329), (292), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Progesterone Receptor antibody is un-conjugated
(20), (17), (16), (12), (12), (12), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(463), (203), (169), (131), (100), (67), (50), (28), (27), (27), (19), (9), (3), (3), (2), (2), (1), (1)
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Product Details anti-Progesterone Receptor Antibody

Target Details Progesterone Receptor Application Details Handling Images
Specificity Equally recognizes two proteins: 116 kDa (triplet) and 86 kDa (singlet) which are identified as the hormone-binding high (B) and low (A) MW forms of Human progesterone receptor. Does not cross-react with Guinea Pig.
Cross-Reactivity (Details) Species reactivity (expected):Baboon, Monkey, Mouse and Rat.
Species reactivity (tested):Human.
Purification Protein G Chromatography
Immunogen Synthetic peptide - KLH conjugated
Clone N-a
Isotype IgG1
Plasmids, Primers & others

Target Details Progesterone Receptor

Product Details anti-Progesterone Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name Progesterone Receptor (PGR Antibody Abstract)
Background The progesterone receptor, a NR3 Steroid Receptor, is induced in granulosa cells of preovulatory follicles in response to surges in luteinizing hormone. It is essential for ovulation and egg implantation. A decrease in expression of endometrial progesterone receptor results in infertility in women. This receptor mediates the progesterone-induced transcription of proteases including ADAMTS1 and cathepsin L. In breast cancer, progesterone receptors are associated with hormone dependence and prolonged survival. At least two alternatively spliced isoforms have been identified in human: hPR-A (94 kD) is 164 aa shorter than hPR-B (114 kD). In most cell contexts, hPR-B functions as a transcriptional activator of progesterone-responsive genes, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors. hPR-A and hPR-B have been shown to regulate different sets of genes in human breast cancer cells. Some of these PR-regulated genes are implicated in breast cancer.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Gene ID 5241
NCBI Accession NP_000917
UniProt P06401
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration

Application Details

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS, pH 7.4 containing 0.2 % BSA as stabilizer and 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Progesterone Receptor (PGR) antibody (ABIN781813) anti-Progesterone Receptor (PGR) antibody