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anti-Human Retinoic Acid Receptor beta Antibodies:
anti-Mouse (Murine) Retinoic Acid Receptor beta Antibodies:
anti-Rat (Rattus) Retinoic Acid Receptor beta Antibodies:
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Human Polyclonal Retinoic Acid Receptor beta Primary Antibody for IHC (p) - ABIN2476325
Haraguchi, Liu, Cianciolo, Good, Day: Suppression of human interferon-gamma production by a 17 amino acid peptide homologous to the transmembrane envelope protein of retroviruses: evidence for a primary role played by monocytes. in Cellular immunology 1992
Show all 3 Pubmed References
Human Monoclonal Retinoic Acid Receptor beta Primary Antibody for EMSA, IHC - ABIN2668691
Chakravarti, Mathur, Bahadur, Shukla, Rochette-Egly, Ralhan: Expression of RARalpha and RARbeta in human oral potentially malignant and neoplastic lesions. in International journal of cancer. Journal international du cancer 2001
Show all 2 Pubmed References
Bat Polyclonal Retinoic Acid Receptor beta Primary Antibody for ELISA, IHC (p) - ABIN4349383
Fabricius, Kruse-Boitschenko, Schneeweiss, Wildner, Hoffmeister, Raguse: Model examination of chemoprevention with retinoids in squamous cell carcinomas of the head and neck region and suitable biomarkers for chemoprevention. in International journal of oncology 2011
Human Polyclonal Retinoic Acid Receptor beta Primary Antibody for ICC, IF - ABIN4349385
Seidensaal, Nollert, Feige, Muller, Fleming, Gunkel, Zaoui, Grabe, Weichert, Weber, Plinkert, Simon, Hess et al.: Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell ... in Molecular cancer 2015
Hypermethylation of RARB gene is associated with high grade lung cancer.
RAR-beta expression state is one of the independent factors for the prognosis of lung squamous cell carcinoma patients
Although studies reported different rates for RAR beta promoter methylation in prostate can tissues, the total meta-analysis demonstrated that RAR beta promoter methylation may be correlated with prostate cancer carcinogenesis and that the RAR beta gene is particularly susceptible.
Hypermethylation frequency of CpG islands in the promoters of retinoic acid receptor beta gene (RAR-beta) gene was respectively 61 and 33% for diffuse and intestinal type n gastric cancer tissues.
There were significant associations between RARB promoter hypermethylation and Oral Cancer risk.
Results indicate that RARbeta hypermethylation correlates well with an increased risk in non-small cell lung cancer (NSCLC) patients. RARbeta gene inactivation caused by RARbeta methylation contributes the NSCLC tumorigenesis and may serve as a potential risk factor, diagnostic marker and drug target of NSCLC. [review]
retinoic acid receptor beta-retinoic X receptor (show xpr1 Antibodies) alpha heterodimer quaternary architecture variable
DBP (show GC Antibodies)(n) are non-toxic to the cells and have a weak overall demethylation effect on genomic DNA. DBP (show GC Antibodies)(n) demethylate the promoter regions of the tumor suppressor genes PTEN and RARB. DBP (show GC Antibodies)(n) promotes expression of the genes RARB, PTEN, CDKN2A, RUNX3 (show RUNX3 Antibodies), Apaf-1 (show APAF1 Antibodies) and APC (show APC Antibodies) "silent" in the MCF-7 because of the hypermethylation of their promoter regions
Data shows that miR (show MLXIP Antibodies)-106a directly targets RARB 3'-UTR (show UTS2R Antibodies) and the miR (show MLXIP Antibodies)-106a-RARB complex promotes the viability of thyroid cancer.
Study identified a novel mutation in RARB gene in patients with intellectual disability and progressive motor impairment which confers gain-of-function further promoting the retinoic acid (RA) ligand-induced transcriptional activity by twofold to threefold over the wild-type receptor. These results providing novel insight into the role of RA in neural networks in humans.
The RARbeta transcriptional targets were particularly enriched for transcripts affected in Huntington's disease.
These findings suggest that the catalytic and scaffolding activities of TDG (show TDG Antibodies) are essential for retinoic acid-dependent gene expression and provide important insights into the mechanisms underlying targeting of TET-TDG (show TDG Antibodies) complexes.
the low expression of RARbeta, may induce the down regulation of p16(INK4a), chronic inflammation and decreased apoptosis and may be involved in vulnerability to HR-HPV and early stage cervical carcinogenesis.
Upregulation of Rarb increases the cytotoxic effect of 5-FU on xenografted cholangiocarcinoma tumors.
Results found that HPV16 E7 increases RARB mRNA and protein expression both in vitro and in the cervix of young K14E7 transgenic mice suggesting that RARB overexpression is part of the early molecular events induced by the E7 oncoprotein.
Chromatin immunoprecipitation assay using RarB as the immunoprecipitation target suggests retinoic acid regulation of Aldh1a3 (show ALDH1A3 Antibodies) and Foxn1 (show FOXN2 Antibodies) in mice.
IL-15 (show IL15 Antibodies) specifically down-regulates RARB expression, and RARB may play a protective role in lung injury caused by smoking or viral infections.
RARB hypermethylation was involved in the areca-associated oral carcinogenesis.
Report liver RAR-beta mediated response to retinoic acid.
Data indicate that all three retinoic acid receptor (show RARA Antibodies) isoforms RARalha, RARbeta and RARgamma are expressed in naive CD8 (show CD8A Antibodies)+ T cells, as well as CD8 (show CD8A Antibodies)+ T cells activated for 48 or 72 h.
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants\; one additional transcript has been described, but its full length nature has not been determined.
retinoic acid receptor, beta
, retinoic acid receptor beta
, retinoic acid receptor beta-like
, HBV-activated protein
, hepatitis B virus activated protein
, nuclear receptor subfamily 1 group B member 2
, retinoic acid receptor beta 2
, retinoic acid receptor beta 4
, retinoic acid receptor beta 5
, retinoic acid receptor beta variant 1
, retinoic acid receptor beta variant 2
, retinoic acid receptor, beta polypeptide
, RAR beta 2
, retinoic acid receptor beta 1/ beta 3
, retinoic acid receptor beta4'
, retinoic acid receptor-beta