P21-Activated Kinase 2 Products
(P21-Activated Kinase 2 (PAK2))
Categories
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008].
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Featured P21-Activated Kinase 2 Categories
P21-Activated Kinase 2 Antibodies
High quality antibodies with extensive validation data.
P21-Activated Kinase 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
P21-Activated Kinase 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended P21-Activated Kinase 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
WB, ELISA, IHC, ICC
Validations
- (2)
- (3)
Cat. No.
ABIN969338
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (4)
Cat. No.
ABIN518609
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7169127
Quantity
100 μL
Datasheet
Datasheet
Recommended P21-Activated Kinase 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380785
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380786
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380316
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended P21-Activated Kinase 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1313923
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570570
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5569891
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our P21-Activated Kinase 2 products
: "P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells." in: Immunology, Vol. 154, Issue 2, pp. 309-321, (2018) (PubMed).: "Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation." in: eLife, Vol. 3, pp. e02270, (2015) (PubMed).
: "Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages." in: Journal of proteome research, Vol. 13, Issue 3, pp. 1270-80, (2014) (PubMed).
: "Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers." in: International journal of cancer. Journal international du cancer, Vol. 132, Issue 5, pp. 1105-13, (2013) (PubMed).
: "Phosphorylation of NLRC4 is critical for inflammasome activation." in: Nature, Vol. 490, Issue 7421, pp. 539-42, (2012) (PubMed).
: "Huntingtin promotes cell survival by preventing Pak2 cleavage." in: Journal of cell science, Vol. 122, Issue Pt 6, pp. 875-85, (2009) (PubMed).
: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, (2007) (PubMed).
: "Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers." in: The Prostate, Vol. 66, Issue 8, pp. 801-10, (2006) (PubMed).
: "Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 17, pp. 6542-7, (2006) (PubMed).
: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, (2004) (PubMed).
Synonyms and alternative names related to P21-Activated Kinase 2
p21 (RAC1) activated kinase 2 (PAK2), p21 protein (Cdc42/Rac)-activated kinase 2 (Pak2), p21 protein (Cdc42/Rac)-activated kinase 2a (pak2a), p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog (pak2.S), p21 (RAC1) activated kinase 2 (Pak2), p21 protein (Cdc42/Rac)-activated kinase 2b (pak2b), 5330420P17Rik, A130002K10Rik, AI836325, cb422, CH73-159L23.1, D16Ertd269e, gamma-PAK, kinase, mKIAA4182, PAK-2, pak2, Pak3, PAK65, pak65, PAKgamma, pakgamma, PAKI, si:dz198m22.1, wu:fb71h01, wu:fc52b03, zgc:91798, zgc:113857Protein level used designations for P21-Activated Kinase 2
- PAK-2
- S6/H4 kinase
- gamma-PAK
- p21 (CDKN1A)-activated kinase 2
- p21-activated kinase 2
- p58
- serine/threonine-protein kinase PAK 2
- redhead
- rhd
- p21 activated kinase 2
- p21-activated kinase I
- p21-activated protein kinase I
- p21 (CDKN1A)-activated kinase 2b
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