anti-Human ATM antibody for Dot Blot

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ATM serine/threonine kinase L homeolog
  • ATM serine/threonine kinase
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • serine/threonine-protein kinase ATM
  • tefu
  • atm.L
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • LOC5565620
  • MGYG_07634
  • PGTG_14279
  • Atm
Epitope
pSer1981
88
36
18
17
17
16
10
6
6
6
6
6
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
368
161
83
28
8
1
1
Host
Rabbit
247
103
11
8
3
1
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
11
11
9
8
7
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Dot Blot (DB), Immunofluorescence (IF)
234
137
122
96
81
57
53
45
27
21
13
8
4
4
2
2
1
1
1
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Catalog No. ABIN389888
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
27.429613 ABIN3030033 DB IF ELISA Rabbit Ig Fraction pSer1981 Log in to see Polyclonal 0
27.429613 ABIN3001850 DB IF/ICC Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1831933 DB Mouse IgG1 Log in to see 543C3a 0
1 ABIN931058 DB Mouse IgG1 Log in to see 543C3a 0
1 ABIN1953664 DB ELISA APC Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1954960 DB ELISA Biotin Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1956110 DB ELISA FITC Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1958437 DB ELISA PE Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1952792 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2206232 DB ELISA Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1957334 DB ELISA HRP Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2617307 DB ELISA Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN1840188 DB IF Rabbit pSer1981 Log in to see Polyclonal 0
1 ABIN2206240 DB ELISA FITC Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2206207 DB ELISA APC Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2206242 DB ELISA PE Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2206241 DB ELISA HRP Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2794243 DB IF Rabbit Ig Fraction pSer1981 Log in to see Polyclonal 0
1 ABIN2206208 DB ELISA Biotin Rabbit IgG pSer1981 Log in to see Polyclonal 0
1 ABIN2206234 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer1981 Log in to see Polyclonal 0

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope pSer1981
(88), (36), (18), (17), (17), (16), (10), (6), (6), (6), (6), (6), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(368), (161), (83), (28), (8), (1), (1)
Host Rabbit
(247), (103), (11), (8), (3), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This ATM antibody is un-conjugated
(11), (11), (9), (8), (7), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Dot Blot (DB), Immunofluorescence (IF)
(234), (137), (122), (96), (81), (57), (53), (45), (27), (21), (13), (8), (4), (4), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM antibody (ABIN389888) Images
Specificity This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Clone RB8121
Isotype Ig Fraction
Plasmids, Primers & others

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM antibody (ABIN389888) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.
Synonyms: Serine-protein kinase ATM, Ataxia telangiectasia mutated, A-T, mutated, ATM
Molecular Weight 350644 DA
Gene ID 472
UniProt Q13315
Pathways p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM antibody (ABIN389888) Images back to top
Application Notes DB = 1:500, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM antibody (ABIN389888) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-ATM antibody (ABIN389888)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Brunet, Gutiérrez-Enríquez, Torres, Bérez, Sanjosé, Galceran, Izquierdo, Menéndez, Gumà, Borràs: "ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations." in: Clinical genetics, Vol. 73, Issue 5, pp. 465-73, 2008

Tsai, Chung, Takahashi, Xu, Hu: "Functional interaction between FOXO3a and ATM regulates DNA damage response." in: Nature cell biology, Vol. 10, Issue 4, pp. 460-7, 2008

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM antibody (ABIN389888) back to top
Supplier Images
Dot Blot (DB) image for anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody (ABIN389888) Dot blot analysis of anti-Phospho-ATM-pS1981 Antibody (ABIN389888) on nitrocellulose ...
Immunofluorescence (IF) image for anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody (ABIN389888) Confocal immunofluorescent analysis ofPhospho-ATM-pS1981 Antibody (ABIN389888) with H...