anti-Human ATM antibody for Immunofluorescence

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ATM serine/threonine kinase L homeolog
  • ATM serine/threonine kinase
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • serine/threonine-protein kinase ATM
  • tefu
  • atm.L
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • LOC5565620
  • MGYG_07634
  • PGTG_14279
  • Atm
Epitope
full length
95
41
18
17
16
15
10
6
6
6
6
6
6
6
6
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
388
166
85
27
8
1
1
Host
Mouse
266
106
11
8
3
Clonality
Monoclonal
Conjugate
This ATM antibody is un-conjugated
11
11
11
10
7
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
256
150
129
94
88
63
57
45
27
22
13
8
4
4
4
2
1
1
1
1
Options
Supplier
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Available images

Catalog No. ABIN151775
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
37.091404 ABIN151030 ICC FACS IF IHC (p) IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 84
19.091406 ABIN151622 ICC IF IHC IP WB Mouse IgG1 Log in to see 5C2 27
19 ABIN363380 ICC FACS IF IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
17.64237 ABIN1869997 IF IHC WB Rabbit IgG pSer1981 Log in to see Polyclonal 0
17.64237 ABIN4902973 ICC IF IHC WB Rabbit IgG Log in to see 0
16.14237 ABIN389888 DB IF Rabbit Ig Fraction pSer1981 Log in to see Polyclonal 3
14.64237 ABIN3030033 DB IF ELISA Rabbit Ig Fraction pSer1981 Log in to see Polyclonal 0
13.14237 ABIN2668604 ICC IF Mouse IgG1 kappa pSer1981 Log in to see 10H11-E-12 3
12.025621 ABIN2134264 IF WB Rabbit Log in to see Polyclonal 0
12.025621 ABIN6135528 IF WB Rabbit Log in to see 0
11.64237 ABIN513576 IF ELISA Mouse IgG2a kappa AA 1-138 Log in to see 2C10 0
9.949036 ABIN151772 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 22
7 ABIN6652959 IF WB Rabbit Ser1981 Log in to see Polyclonal 4
7 ABIN6267798 ELISA ICC IF WB Rabbit IgG AA 1979-1983 Log in to see Polyclonal 0
7 ABIN1882297 IF WB Rabbit IgG Log in to see Polyclonal 0
5.5 ABIN362751 IF WB Rabbit IgG AA 1979-1983 Log in to see Polyclonal 5
4 ABIN2852418 ICC IF IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 0
4 ABIN5573135 IF IHC (p) IP WB Mouse IgG1 Log in to see 2C1 0
4 ABIN6719142 ICC IF IHC WB Rabbit Log in to see 0
4 ABIN6580329 IF WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope full length
(95), (41), (18), (17), (16), (15), (10), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(388), (166), (85), (27), (8), (1), (1)
Host Mouse
(266), (106), (11), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ATM antibody is un-conjugated
(11), (11), (11), (10), (7), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(256), (150), (129), (94), (88), (63), (57), (45), (27), (22), (13), (8), (4), (4), (4), (2), (1), (1), (1), (1)
Pubmed 117 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM antibody (ABIN151775) Images
Specificity This antibody recognizes full-length ATM, a 350- kDa nuclear phosphoprotein.
Purification Protein G purified
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Clone 2C1
Isotype IgG1
Plasmids, Primers & others

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM antibody (ABIN151775) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background Gene Symbol: ATM
Molecular Weight Theoretical MW: 370 kDa
Gene ID 472
UniProt Q13315
Pathways p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM antibody (ABIN151775) Images back to top
Application Notes Western Blot 1:500-1:3000, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry, ELISA 1:100 - 1:2000, Immunohistochemistry 10 - 1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1-10 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLIHC-R. ICC/IF usage reported in scientifc literature (Harry Scherthan, et.al., 2000 and Yiyoung Liu, et.al., 2006). ELISA usage reported in scientific literature. WB: Predicted molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM antibody (ABIN151775) Images back to top
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS ( pH 7.4)
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

References for anti-ATM antibody (ABIN151775)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Product cited in:

Fu, Zhang, Meng, Zhang, Shi, Cao, Wang, Su, Xin, Ren, Zhang, Sun, Ge, Silvennoinen, Yao, Yang, Yang: "Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress." in: Cell death and differentiation, Vol. 25, Issue 9, pp. 1625-1637, 2018

Göder, Emmerich, Nikolova, Kiweler, Schreiber, Kühl, Imhof, Christmann, Heinzel, Schneider, Krämer: "HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130." in: Nature communications, Vol. 9, Issue 1, pp. 764, 2018

Belužić, Grbeša, Belužić, Park, Kong, Kopjar, Espadas, Sabidó, Lepur, Rokić, Jerić, Brkljačić, Vugrek: "Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest." in: Scientific reports, Vol. 8, Issue 1, pp. 14012, 2018 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Simões, Martins, Ferreira: "Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus." in: Virus research, Vol. 210, pp. 1-7, 2015

Park, Kong, Kim, Lee, Park: "Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest." in: American journal of cancer research, Vol. 5, Issue 7, pp. 2127-38, 2015 Further details: Western Blotting

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting

Vermezovic, Adamowicz, Santarpia, Rustighi, Forcato, Lucano, Massimiliano, Costanzo, Bicciato, Del Sal, dAdda di Fagagna: "Notch is a direct negative regulator of the DNA-damage response." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 417-24, 2015 (Sample species: Human). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Muraki, Han, Miller, Murnane: "Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks." in: Nucleic acids research, Vol. 43, Issue 16, pp. 7911-30, 2015 (Sample species: Human). Further details: Western Blotting

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (Sample species: Human). Further details: Western Blotting

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, 2013 (Sample species: Mouse (Murine)). Further details: Western Blotting

Murad, Cullen, McKenzie, Ryan, Thorburn, Gueven, Kobayashi, Birrell, Yang, Dörk, Becherel, Grattan-Smith, Lavin: "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia." in: Mitochondrion, Vol. 13, Issue 3, pp. 235-45, 2013 (Sample species: Human). Further details: Western Blotting

Simões, Martins, Ferreira: "Host DNA damage response facilitates African swine fever virus infection." in: Veterinary microbiology, Vol. 165, Issue 1-2, pp. 140-7, 2013

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." in: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 Further details: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (Sample species: Human). Further details: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." in: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (Sample species: Human). Further details: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (Sample species: Human). Further details: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (Sample species: Human). Further details: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." in: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (Sample species: Human). Further details: Western Blotting

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM antibody (ABIN151775) back to top
Supplier Images
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug U87-MG whole cell lysate/ext...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug NT2D1 whole cell lysate/extr...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - analysis of ATM in U2OS sarcoma cells...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Testis (formal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Kidney (formal...