anti-Human ATR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ATR Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia and Rad3 Related (ATR) Antibodies
  • ATR
  • si:dkey-231j24.1
  • FCTCS
  • FRP1
  • MEC1
  • SCKL
  • SCKL1
  • XATR
  • frp1
  • mec1
  • sckl
  • sckl1
  • ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED
  • ATATR
  • ATRAD3
  • Ataxia telangiectasia-mutated and RAD3-related
  • MHK7.5
  • MHK7_5
  • ataxia telangiectasia and Rad3 related
  • ATR serine/threonine kinase
  • ATR serine/threonine kinase L homeolog
  • Ataxia telangiectasia-mutated and RAD3-like protein
  • Atr
  • ATR
  • atr
  • atr.L
Epitope
AA 2545-2645
2
1
1
1
1
Reactivity
Human
9
5
2
1
1
1
1
1
1
Host
Mouse
9
1
Clonality
Monoclonal
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
8
2
2
1
1
1
1
Supplier
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Catalog No. ABIN614390
$ 445.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN319379 IHC (p) Rabbit Ser428 Log in to see Polyclonal 4

General

Antigen Ataxia Telangiectasia and Rad3 Related (ATR) Antibodies
Epitope AA 2545-2645
(2), (1), (1), (1), (1)
Reactivity Human
(9), (5), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(9), (1)
Clonality (Clone)
Monoclonal   ( )
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(8), (2), (2), (1), (1), (1), (1)
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Product Details anti-ATR Antibody

Target Details ATR Application Details Handling Images
Specificity Recognizes Ataxia Telangiectasia and Rad3 Related (ATR)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein A Chromatography
Immunogen aTR (NP_001175, 2545 a.a. ~ 2645 a.a) partial recombinant protein with GST tag.
Clone 1-00E-009
Isotype IgG2a
Plasmids, Primers & others

Target Details ATR

Product Details anti-ATR Antibody Application Details Handling Images back to top
Antigen
Alternative Name ATR / FRP1 (ATR Antibody Abstract)
Background The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.Synonyms: Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, Serine/threonine-protein kinase ATR
Gene ID 545
NCBI Accession NP_001175
UniProt Q13535
Pathways p53 Signaling, Apoptosis, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-ATR Antibody Target Details ATR Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ATR Antibody Target Details ATR Application Details Images back to top
Buffer PBS, pH 7.2
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

Images

Product Details anti-ATR Antibody Target Details ATR Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2545-2645) antibody (ABIN614390) anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2545-2645) antibody
Immunohistochemistry (IHC) image for anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2545-2645) antibody (ABIN614390) anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2545-2645) antibody (Image 2)