anti-Human BAX antibody for Immunocytochemistry

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Reactivity
Human, Mouse (Murine), Rat (Rattus)
555
232
212
128
44
31
28
23
21
11
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
346
243
4
2
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
14
12
11
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
453
229
193
167
143
140
113
46
42
40
32
26
13
5
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN6260205
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN6260204 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 3
1 ABIN451743 ELISA FACS ICC IF IHC IHC (fro) IP WB Mouse IgG1 kappa N-Term Log in to see 6A7 3
1 ABIN4283106 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa AA 3-16 Log in to see 2D2 1
1 ABIN5949410 ICC IF IHC IHC (p) WB Rabbit IgG N-Term Log in to see Rabbit Polyclonal Antibody 0
1 ABIN213905 ICC IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1001866 ICC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal 4
1 ABIN1866865 ICC IHC WB Rabbit IgG AA 1-192 Log in to see Polyclonal 0
1 ABIN1978903 ELISA ICC IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 0
1 ABIN1732229 ICC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN4283109 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN5773948 ELISA ICC IP WB Rabbit IgG AA 13-36 Log in to see G26-R 0
1 ABIN4283131 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 405 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283132 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283139 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 488 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283146 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 405 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283137 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 650 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283144 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 550 Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283136 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Biotin Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN4283130 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN5774047 ELISA ICC IHC (fro) IHC (p) IP WB Rabbit N-Term Log in to see G26-R 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(555), (232), (212), (128), (44), (31), (28), (23), (21), (11), (7), (7), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(346), (243), (4), (2)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (14), (12), (11), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(453), (229), (193), (167), (143), (140), (113), (46), (42), (40), (32), (26), (13), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 11 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN6260205) Images
Specificity Bax antibody detects endogenous levels of total Bax
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human Bax
Isotype IgG
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN6260205) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background

Description: Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Gene: BAX

Molecular Weight 21kDa
Gene ID 581
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN6260205) Images back to top
Application Notes WB: 1:500~1:3000 IHC: 1:50~1:200 IF 1:200
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN6260205) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, glycerol.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

References for anti-BAX antibody (ABIN6260205)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo, Guo: "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." in: Frontiers in microbiology, Vol. 8, pp. 1697, 2018

Lu, Zhou, Hao, Li, Wang, Shu, Du, Zhu, Zhang, Yin: "The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy." in: Molecular and cellular endocrinology, Vol. 473, pp. 31-43, 2018

Shao, Zhang, Ma, Lu, Meng, Li, Wang, Chen, Zhang, Han, Liu, Ma: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, 2018

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, 2018

Zhou, Zhang, Liu, Lei, Liu, Jiao, Dang: "Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice." in: Frontiers in behavioral neuroscience, Vol. 12, pp. 110, 2018

Wang, Li, Chen, Luo, Gu, Wang, Wu, Xu et al.: "Baicalin extracted from Huangqin (Radix Scutellariae Baicalensis) induces apoptosis in gastric cancer cells by regulating B cell lymphoma (Bcl-2)/Bcl-2-associated X protein and activating caspase-3 ..." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, Vol. 37, Issue 2, pp. 229-5, 2018

Liu, Zheng, Zhang, Wang, Yang, Bai, Dai: "Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells." in: Neurochemical research, Vol. 41, Issue 10, pp. 2728-2751, 2017

Zhao, Deng, Xu, Zhang, Mi, Meng, Gou, Xu: "PirB Overexpression Exacerbates Neuronal Apoptosis by Inhibiting TrkB and mTOR Phosphorylation After Oxygen and Glucose Deprivation Injury." in: Cellular and molecular neurobiology, Vol. 37, Issue 4, pp. 707-715, 2017

Gu, Yang, Qi, Mei, Chen, Song, Jing, Chen, He, Sun, Hu, Li, Wüthrich, Wu, Mei: "Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis." in: Kidney & blood pressure research, Vol. 41, Issue 6, pp. 848-864, 2017

Chen, Wu, Gan, Liu, Lv, Shen, Dai, Xu: "Iridoid glycoside from Cornus officinalis ameliorated diabetes mellitus-induced testicular damage in male rats: Involvement of suppression of the AGEs/RAGE/p38 MAPK signaling pathway." in: Journal of ethnopharmacology, Vol. 194, pp. 850-860, 2017

Liu, Liu, He, Zhang, Liu, Wang, Qiu, Xu, Xiang, Lv: "Differential gene and lncRNA expression in the lower thoracic spinal cord following ischemia/reperfusion-induced acute kidney injury in rats." in: Oncotarget, Vol. 8, Issue 32, pp. 53465-53481, 2017

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN6260205) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) Western blot analysis on HepG2 cell lysate using Bax Antibody,The lane on the left is...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) ABIN6266500 staining lovo cells by ICC/IF. Cells were fixed with PFA and permeabilize...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) Western blot analysis on rat liver tissue lysate using Bax Antibody