anti-Human BAX antibody for Immunohistochemistry

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Epitope
AA 143-192, pSer184
106
65
31
22
21
19
15
15
13
12
11
10
10
10
8
8
5
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
501
219
200
89
47
35
30
28
22
9
8
8
5
3
3
2
1
1
1
1
Host
Rabbit
322
209
4
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
14
13
11
10
8
7
6
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Immunohistochemistry (IHC), ELISA
395
216
143
140
123
118
102
48
40
37
13
9
5
5
4
2
1
1
1
1
1
1
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Catalog No. ABIN1532125
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.0975895 ABIN2707357 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
9.0975895 ABIN2705572 IC IF IHC ELISA WB Rabbit Center Log in to see Polyclonal 0
9.0975895 ABIN2705573 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
9.0975895 ABIN1533155 IHC ELISA Rabbit IgG AA 143-192 Log in to see Polyclonal 2
9.0975895 ABIN1534427 IHC ELISA Rabbit IgG AA 10-59 Log in to see Polyclonal 2
9.0975895 ABIN1534428 IF IHC ELISA Rabbit IgG AA 80-129 Log in to see Polyclonal 2
9.0975895 ABIN1534426 IF IHC ELISA WB Rabbit IgG AA 41-90 Log in to see Polyclonal 2
9.0975895 ABIN2707358 IHC WB Rabbit N-Term Log in to see Polyclonal 0
9.0975895 ABIN1871227 IHC WB Rabbit IgG Log in to see Polyclonal 0
9.0975895 ABIN3026586 FACS IF IP IHC ELISA WB Mouse IgG1 Log in to see 2D2 0
9.0975895 ABIN1585631 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
9.0975895 ABIN2470036 IP IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0
9.0975895 ABIN2470569 IP IHC WB Mouse IgG1 Log in to see 6A7 0
9.0975895 ABIN3025800 FACS IF IHC WB Mouse IgG1 AA 3-16 Log in to see SPM336 0
9.0975895 ABIN3030145 FACS IHC ELISA WB Rabbit Ig Fraction AA 41-76 Log in to see Polyclonal 0
9.0975895 ABIN2427569 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
9.0975895 ABIN1848438 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
9.0975895 ABIN1850412 ELISA IF/ICC IHC Rabbit Internal Region Log in to see Polyclonal 0
1 ABIN2792125 IHC WB Rabbit N-Term Log in to see Polyclonal 3
1 ABIN4283106 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa AA 3-16 Log in to see 2D2 1

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope AA 143-192, pSer184
(106), (65), (31), (22), (21), (19), (15), (15), (13), (12), (11), (10), (10), (10), (8), (8), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(501), (219), (200), (89), (47), (35), (30), (28), (22), (9), (8), (8), (5), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(322), (209), (4)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (14), (13), (11), (10), (8), (7), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Immunohistochemistry (IHC), ELISA
(395), (216), (143), (140), (123), (118), (102), (48), (40), (37), (13), (9), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN1532125) Images
Specificity

Bax (Phospho-Ser184) Antibody detects endogenous levels of Bax only when phosphorylated at Ser184.

PhosphorylationH:S184 M:S184 R:S184

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.
Isotype IgG

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN1532125) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background

Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4

NCBI Gene Symbol: BAX

Molecular Weight 21 kDa
Gene ID 581
OMIM 600040
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN1532125) Images back to top
Application Notes IHC: 1:50~1:100 ELISA: 1:10000
Comment

Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)

Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN1532125) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months

References for anti-BAX antibody (ABIN1532125)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, 2013

Background publications

Apte, Mattei, Olsen: "Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta." in: Genomics, Vol. 26, Issue 3, pp. 592-4, 1995

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN1532125) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 143-192), (pSer184) antibody (ABIN1532125) Immunohistochemistry analysis of paraffin-embedded human brain, using Bax (Phospho-Se...