anti-Human BAX antibody for Immunoprecipitation

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Epitope
N-Term
92
77
31
22
21
17
15
13
12
12
10
10
10
10
10
7
7
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
556
239
217
122
42
31
26
23
21
9
6
5
5
3
3
2
1
1
1
1
Host
Rabbit
351
241
4
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
15
13
12
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
454
233
195
158
144
143
121
45
42
40
34
26
13
5
5
2
2
1
1
1
1
1
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Catalog No. ABIN222887
$ 245.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4283098 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 3
1 ABIN451743 ELISA FACS ICC IF IHC IHC (fro) IP WB Mouse IgG1 kappa N-Term Log in to see 6A7 3
1 ABIN4283096 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 2
1 ABIN241547 IHC IHC (p) IP WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN957152 IHC IHC (fro) IHC (p) IP WB Rabbit AA 43-61 Log in to see Polyclonal 0
1 ABIN205493 IP IHC WB Mouse IgG1 AA 3-16 Log in to see 2D2 0
1 ABIN337236 IHC IHC (p) IP Mouse IgG1 Log in to see 6A7 0
1 ABIN126979 IP WB Rabbit N-Term Log in to see Polyclonal 2
1 ABIN372361 IHC (p) IP WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN2736349 FACS IF IP IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1732230 IHC (p) IP WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN2208719 FACS IF IP IHC ELISA WB Mouse IgG1 AA 3-16 Log in to see 2D2 0
1 ABIN1001865 IP WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN3026586 ELISA FACS IF IHC (p) IP WB Mouse IgG1 Log in to see 2D2 0
1 ABIN1978903 ELISA ICC IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 0
1 ABIN1724048 IHC (p) IP WB Mouse IgG1 Log in to see 6A7 0
1 ABIN5563785 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN241613 IP WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN4283109 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 AA 3-16 Log in to see SPM336 0
1 ABIN2470036 IP IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope N-Term
(92), (77), (31), (22), (21), (17), (15), (13), (12), (12), (10), (10), (10), (10), (10), (7), (7), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(556), (239), (217), (122), (42), (31), (26), (23), (21), (9), (6), (5), (5), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(351), (241), (4)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (15), (13), (12), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunoprecipitation (IP), Western Blotting (WB)
(454), (233), (195), (158), (144), (143), (121), (45), (42), (40), (34), (26), (13), (5), (5), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN222887) Images
Blocking Peptide Blocking peptide for this product available: ABIN412605
Specificity The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE immunoblots.
Purification Affinity purified
Immunogen Synthetic peptide corresponding to AA near the N-terminus of human Bax
Isotype IgG
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN222887) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with Bcl-2. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death.
Synonyms: 581, BAX, 600040, P55269, Bax zeta
Gene ID 581
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN222887) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL), immunoprecipitation (10-20 μg/mL). However, the optimal conditions should be determined individually.The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE immunoblots.
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN222887) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-Bax polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-BAX antibody (ABIN222887)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Eslami, Sharifi, Rahimi, Rahati: "Protective effect of telmisartan against oxidative damage induced by high glucose in neuronal PC12 cell." in: Neuroscience letters, 2013

Jafari Anarkooli, Sankian, Vahedi, Bonakdaran, Varasteh, Haghir: "Evaluation of insulin and ascorbic acid effects on expression of Bcl-2 family proteins and caspase-3 activity in hippocampus of STZ-induced diabetic rats." in: Cellular and molecular neurobiology, Vol. 29, Issue 1, pp. 133-40, 2009

Mousavi, Tavakkol-Afshari, Brook, Jafari-Anarkooli: "Direct toxicity of Rose Bengal in MCF-7 cell line: role of apoptosis." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 47, Issue 4, pp. 855-9, 2009

Maity, Bindu, Choubey, Alam, Mitra, Goyal, Dey, Guha, Pal, Bandyopadhyay et al.: "Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent ..." in: The Journal of biological chemistry, Vol. 283, Issue 21, pp. 14391-401, 2008

Kim, Zhang, Hitomi, Lee, Mukherjee: "Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL." in: Human molecular genetics, Vol. 15, Issue 11, pp. 1826-34, 2006

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN222887) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN222887) Western blot analysis of Bax expression in rat kidney tissue lysate.