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|Antigen||BCL2-Associated X Protein (BAX) Antibodies|
|Reactivity||Cow (Bovine), Human, Monkey, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This BAX antibody is un-conjugated Alternatives|
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
|8 references available|
Product Details anti-BAX AntibodyTarget Details BAX Application Details Handling References for anti-BAX antibody (ABIN451743) Images
|Specificity||The monoclonal antibody 6A7 reacts with human, mouse and rat Bax but does not bind the soluble cytosolic form of Bax, however, treatment of cells with non-ionic detergents exposes the epitope and allows binding of 6A7 to monomeric forms of Bax but not Bax complexed with either Bcl-2 or Bcl-xL.|
|Purification||Protein A or G purified|
|Immunogen||KLH-conjugated peptide corresponding to amino acids 12-24 located near the N-terminus common to human, mouse and rat Bax.|
|Plasmids, Primers & others|
Target Details BAXProduct Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN451743) Images back to top
|Alternative Name||Bax (BAX Antibody Abstract)|
|Background||Gene Symbol: BAX|
|Pathways||p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response|
Application DetailsProduct Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN451743) Images back to top
|Application Notes||Western Blot < = 1 μg/mL, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500|
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN451743) Images back to top
Borate buffered saline, pH 8.2
Buffer contains: No Preservative
|Handling Advice||Do not freeze.|
|Storage Comment||Store at 4°C. Do not freeze.|
References for anti-BAX antibody (ABIN451743)Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
|Product cited in:||
Xu, Chen, Wang, Wang, Miao, Yin, Cheng, Zhou, Xie, Zhou, Liu, Wang, Zent, Lu, Zhang: "NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury." in: American journal of physiology. Renal physiology, Vol. 316, Issue 2, pp. F382-F395, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).
Yu, Li, Chen, Lai, Lin, Korla, Chai, Ko, Chen, Hwang, Lee, Sheu: "YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis." in: The Journal of pathology, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Zhou, Liu, Lin, Xu, Mao, Liu, Zhang, Jiang, Zhou: "Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 25, pp. 836-846, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Zheng, Matei, Pang, Luo, Song, Tang, Zhang: "Delayed recanalization at 3 days after permanent MCAO attenuates neuronal apoptosis through FGF21/FGFR1/PI3K/Caspase-3 pathway in rats." in: Experimental neurology, Vol. 320, pp. 113007, 2019 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).
Gong, Xu, Zi, Chen: "miR-625 reverses multidrug resistance in gastric cancer cells by directly targeting ALDH1A1." in: Cancer management and research, Vol. 11, pp. 6615-6624, 2019 Method employed by authors: Functional Studies (Func) (Sample species: Human).
Barreto-Vianna, Aguila, Mandarim-de-Lacerda: "Effects of liraglutide in hypothalamic arcuate nucleus of obese mice." in: Obesity (Silver Spring, Md.), Vol. 24, Issue 3, pp. 626-33, 2016 Further details: Western Blotting
Shi, Xu, Doycheva, Tang, Yan, Zhang: "Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016
Xie, Enkhjargal, Wu, Zhou, Sun, Hu, Gospodarev, Tang, You, Zhang: "Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats." in: Neuropharmacology, Vol. 128, pp. 142-151, 1970 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).
ImagesProduct Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN451743) back to top