anti-Mouse (Murine) BAX antibody for Immunofluorescence

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Reactivity
Human, Mouse (Murine), Rat (Rattus)
556
232
212
128
44
31
28
23
21
11
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
347
243
4
2
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
14
12
11
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
454
229
194
167
143
140
113
46
42
40
32
26
13
5
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN6260205
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.066742 ABIN6254209 IF WB Goat IgG N-Term Log in to see Polyclonal 0
18.758589 ABIN3183484 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
15.758589 ABIN3183483 ELISA IF IHC Rabbit IgG Internal Region Log in to see Polyclonal 0
15.758589 ABIN3183486 ELISA IF WB Rabbit IgG Ser165 Log in to see Polyclonal 0
14.308153 ABIN2705573 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
14.308153 ABIN1534426 IF IHC ELISA WB Rabbit IgG AA 41-90 Log in to see Polyclonal 2
14.308153 ABIN1574983 IF IHC ELISA WB Rabbit Log in to see Polyclonal 0
12.808153 ABIN1531490 IF ELISA Rabbit IgG AA 133-182, pThr167 Log in to see Polyclonal 5
12.758589 ABIN3183038 ELISA IF Rabbit IgG pThr167 Log in to see Polyclonal 0
12.758589 ABIN2134521 IF ELISA Rabbit IgG pThr167 Log in to see Polyclonal 0
11.5 ABIN6260204 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 3
11.308153 ABIN2957872 IC IF WB Rabbit C-Term Log in to see Polyclonal 0
11.308153 ABIN1532504 IF ELISA WB Rabbit IgG AA 133-182 Log in to see Polyclonal 2
11.308153 ABIN1534428 IF IHC ELISA Rabbit IgG AA 80-129 Log in to see Polyclonal 2
11.308153 ABIN5611595 EIA IF IHC (p) Rabbit IgG AA 145-157, Internal Region Log in to see Polyclonal 0
11.308153 ABIN1574979 IF ELISA Rabbit pThr167 Log in to see Polyclonal 0
7 ABIN2888759 IF ELISA WB Rabbit IgG AA 133-182 Log in to see Polyclonal 0
7 ABIN2889978 ELISA IF IHC WB Rabbit IgG AA 41-90 Log in to see Polyclonal 0
7 ABIN1574981 IF IHC ELISA Rabbit Log in to see Polyclonal 0
4 ABIN2889980 ELISA IF IHC Rabbit IgG AA 80-129 Log in to see Polyclonal 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(556), (232), (212), (128), (44), (31), (28), (23), (21), (11), (7), (7), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(347), (243), (4), (2)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (14), (12), (11), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(454), (229), (194), (167), (143), (140), (113), (46), (42), (40), (32), (26), (13), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 11 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN6260205) Images
Specificity Bax antibody detects endogenous levels of total Bax
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human Bax
Isotype IgG
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN6260205) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background

Description: Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Gene: BAX

Molecular Weight 21kDa
Gene ID 581
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN6260205) Images back to top
Application Notes WB: 1:500~1:3000 IHC: 1:50~1:200 IF 1:200
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN6260205) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, glycerol.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

References for anti-BAX antibody (ABIN6260205)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo, Guo: "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." in: Frontiers in microbiology, Vol. 8, pp. 1697, 2018

Lu, Zhou, Hao, Li, Wang, Shu, Du, Zhu, Zhang, Yin: "The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy." in: Molecular and cellular endocrinology, Vol. 473, pp. 31-43, 2018

Shao, Zhang, Ma, Lu, Meng, Li, Wang, Chen, Zhang, Han, Liu, Ma: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." in: Gene, Vol. 652, pp. 48-58, 2018

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, 2018

Zhou, Zhang, Liu, Lei, Liu, Jiao, Dang: "Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice." in: Frontiers in behavioral neuroscience, Vol. 12, pp. 110, 2018

Wang, Li, Chen, Luo, Gu, Wang, Wu, Xu et al.: "Baicalin extracted from Huangqin (Radix Scutellariae Baicalensis) induces apoptosis in gastric cancer cells by regulating B cell lymphoma (Bcl-2)/Bcl-2-associated X protein and activating caspase-3 ..." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, Vol. 37, Issue 2, pp. 229-5, 2018

Liu, Zheng, Zhang, Wang, Yang, Bai, Dai: "Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells." in: Neurochemical research, Vol. 41, Issue 10, pp. 2728-2751, 2017

Zhao, Deng, Xu, Zhang, Mi, Meng, Gou, Xu: "PirB Overexpression Exacerbates Neuronal Apoptosis by Inhibiting TrkB and mTOR Phosphorylation After Oxygen and Glucose Deprivation Injury." in: Cellular and molecular neurobiology, Vol. 37, Issue 4, pp. 707-715, 2017

Gu, Yang, Qi, Mei, Chen, Song, Jing, Chen, He, Sun, Hu, Li, Wüthrich, Wu, Mei: "Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis." in: Kidney & blood pressure research, Vol. 41, Issue 6, pp. 848-864, 2017

Chen, Wu, Gan, Liu, Lv, Shen, Dai, Xu: "Iridoid glycoside from Cornus officinalis ameliorated diabetes mellitus-induced testicular damage in male rats: Involvement of suppression of the AGEs/RAGE/p38 MAPK signaling pathway." in: Journal of ethnopharmacology, Vol. 194, pp. 850-860, 2017

Liu, Liu, He, Zhang, Liu, Wang, Qiu, Xu, Xiang, Lv: "Differential gene and lncRNA expression in the lower thoracic spinal cord following ischemia/reperfusion-induced acute kidney injury in rats." in: Oncotarget, Vol. 8, Issue 32, pp. 53465-53481, 2017

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN6260205) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) Western blot analysis on HepG2 cell lysate using Bax Antibody,The lane on the left is...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) ABIN6266500 staining lovo cells by ICC/IF. Cells were fixed with PFA and permeabilize...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) antibody (ABIN6260205) Western blot analysis on rat liver tissue lysate using Bax Antibody