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|Antigen||BCL2-Associated X Protein (BAX) Antibodies|
|Reactivity||Dog (Canine), Human, Monkey, Orang-Utan (Pongo abelii), Pig (Porcine) Alternatives|
|Conjugate||This BAX antibody is un-conjugated Alternatives|
ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-BAX AntibodyTarget Details BAX Application Details Handling Images
|No Cross-Reactivity||Mouse (Murine), Rat (Rattus)|
|Purification||Protein G purified|
Amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Baboon, Monkey, Ferret, Cat, Pig, Dog (100%), Bat, Elephant (93%).
Type of Immunogen: Synthetic peptide
Target Details BAXProduct Details anti-BAX Antibody Application Details Handling Images back to top
|Alternative Name||BAX (BAX Antibody Abstract)|
Name/Gene ID: BAX
Synonyms: BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
|Pathways||p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response|
Application DetailsProduct Details anti-BAX Antibody Target Details BAX Handling Images back to top
Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes a protein of 21 kDa, identified as the Bax protein. The Bax antibody is highly specific and shows no cross-reaction with Bcl-2 alpha or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and the protein also counters the death repressor activity of Bcl-2. ELISA: Order BSA-free format for coating.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BAX Antibody Target Details BAX Application Details Images back to top
|Buffer||PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at 2-8°C.|