anti-Rat (Rattus) BAX antibody for Immunofluorescence (Cultured Cells)

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Epitope
AA 60-110
89
77
30
22
21
19
15
13
12
12
11
10
9
9
9
7
7
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
556
232
213
128
43
31
27
23
21
11
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
347
243
4
2
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
14
12
11
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
454
230
194
168
142
139
113
47
42
39
32
26
12
5
5
2
2
1
1
1
1
1
1
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Catalog No. ABIN725390
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN725397 FACS IF (cc) IF (p) FITC Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN725393 FACS IF (cc) IF (p) Cy3 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN725394 FACS IF (cc) IF (p) Cy5 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN725395 FACS IF (cc) IF (p) Cy5.5 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN725396 FACS IF (cc) IF (p) Cy7 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN884558 FACS IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN884565 FACS IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN884559 FACS IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN884561 FACS IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN2808095 FACS IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN4997214 FACS IF (cc) IF (p) Alexa Fluor 680 Rabbit IgG AA 60-110 Log in to see Polyclonal 0
1 ABIN4997215 FACS IF (cc) IF (p) Alexa Fluor 750 Rabbit IgG AA 60-110 Log in to see Polyclonal 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope AA 60-110
(89), (77), (30), (22), (21), (19), (15), (13), (12), (12), (11), (10), (9), (9), (9), (7), (7), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(556), (232), (213), (128), (43), (31), (27), (23), (21), (11), (7), (7), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(347), (243), (4), (2)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (14), (12), (11), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(454), (230), (194), (168), (142), (139), (113), (47), (42), (39), (32), (26), (12), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 24 references available
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Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN725390) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Bax
Isotype IgG
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN725390) Images back to top
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Subcellular location: Mitochondrion

Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX

Gene ID 581
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN725390) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN725390) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-BAX antibody (ABIN725390)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Liu, Li, Yang, Niu, Zhao, Zhao, Wang: "Valproic acid attenuates inflammation of optic nerve and apoptosis of retinal ganglion cells in a rat model of optic neuritis." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 1363-1370, 2018 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: optic nerve

Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: liver

Rahman, Ukiana, Uson-Lopez, Sikder, Saito, Kurasaki: "Cytotoxic effects of cadmium and zinc co-exposure in PC12 cells and the underlying mechanism." in: Chemico-biological interactions, Vol. 269, pp. 41-49, 2017 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)).

Liu, Su, Hao, Chen, Liu, Liao, Li: "Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice." in: International journal of molecular sciences, Vol. 17, Issue 1, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: testis

Aksu, Özkaraca, Kandemir, Ömür, Eldutar, Küçükler, Çomaklı: "Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress." in: Andrologia, Vol. 48, Issue 10, pp. 1145-1154, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: Testis

Daverey, Agrawal: "Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes." in: Neuroscience, Vol. 333, pp. 92-103, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Yang, Lu, Guo: "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4075-4082, 2016 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Rat (Rattus)).

She, Zhao, Zhu, Han, Xia, Bai, Zhang, Li: "Aluminum Trichloride Disorders Bile Acid Secretion and Induces Hepatocyte Apoptosis in Rats." in: Cell biochemistry and biophysics, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: Liver

Huang, Zou, Shi, Zhang, Peng, Zhang, Gao, Wang, Zhang: "Electroacupuncture stimulates remodeling of extracellular matrix by inhibiting apoptosis in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 386012, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Rabbit).

Li, Zhang, Liu, Ren, Song, Rao, Takahashi, Zhou, Li, Chen: "Deficits of learning and memory in Hemojuvelin knockout mice." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: Brain

Park, Kim, Choi, Heo, Park: "New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro." in: Cellular signalling, Vol. 27, Issue 9, pp. 1831-9, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

He, Han, Hu, Zhang, Hua, Peng: "Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs)." in: Cell and tissue research, Vol. 362, Issue 2, pp. 379-88, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Pig (Porcine)).

He, Song, Liu, Chen, Hua: "Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells." in: Cell proliferation, Vol. 47, Issue 2, pp. 161-71, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Ye, Li, Li, Yang, Niu, Wang: "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." in: Journal of ethnopharmacology, Vol. 153, Issue 1, pp. 258-67, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Lin, Wang, Wang, Fang, Zhang, Yang, Guo, Lin, Zhang, Wang: "Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo." in: Nutrition and cancer, Vol. 66, Issue 4, pp. 613-24, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Zhu, Wang, Liang, Wang, Zhang, Li, Ying: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Lin, Bo, Tan, Sun, Song, Zhao, Ma, Li, Zheng, Xu: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: Brain

Wang, Lu, Dai, Zhang, Wang, Wei: "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], 2014 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Mouse (Murine)).

Qiu, Cai, Gao, Gu, Liu: "A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53." in: Cancer letters, Vol. 356, Issue 2 Pt B, pp. 910-7, 2014 Method employed by authors: Immunoprecipitation (IP) (Sample species: Human).

Tian, Zhang, Wang, Dai, Shen, Yang, Huang: "The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25-35-induced oxidative stress and neuronal apoptosis in rats." in: Behavioural brain research, Vol. 242, pp. 1-8, 2013 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)). Further details: Sample: brain

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN725390) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclo...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclon...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded rabbit brain tissue labeled with Anti-Bax Polycl...
SDS-PAGE (SDS) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) L1 rat brain, L2 mouse liver lysates probed (ABIN725390) at 1:200 in 4 °C. Followed b...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Paraformaldehyde-fixed, paraffin embedded rat lung; Antigen retrieval by boiling in s...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Bax Polyclon...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Formalin-fixed and paraffin embedded rabbit brain tissue labeled with Anti-Bax Polycl...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) L1 rat brain, L2 mouse liver lysates probed at 1:200 in 4˚C. Followed by conjugation...
Flow Cytometry (FACS) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Human HL-60 cells probed with Bax Polyclonal Antibody, Unconjugated (green) at 1:30 ...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Image provided by One World Lab validation program. A431 cells probed with Rabbit Ant...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-BCL2-Associated X Protein (BAX) (AA 60-110) antibody (ABIN725390) Image provided by One World Lab validation program. MCF-7 cells probed with Rabbit An...