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|Antigen||V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies|
|Conjugate||This C-MYC antibody is un-conjugated Alternatives|
Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
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Product Details anti-C-MYC AntibodyTarget Details C-MYC Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||Synthetic peptide derived from human c-Myc(S62), around 50-100aa (phospho S62).|
Target Details C-MYCProduct Details anti-C-MYC Antibody Application Details Handling Images back to top
|Alternative Name||c-Myc (MYC Antibody Abstract)|
Epitope tags are useful for the labeling and detection of proteins usingimmunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged protein's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast,insect and mammalian cell systems.The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Synonyms: Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, c Myc Epitope Tag, c Myc Tag, Cellular myelocytomatosis oncogene, MGC105490, MRTL, Myc Epitope Tag, Myc protein, Myc proto oncogene protein, Myc proto-oncogene protein, Myc-related translation/localization regulatory factor, Myc2, myca, Myelocytomatosis oncogene a, Myelocytomatosis oncogene, Niard, Nird, Oncogene Myc, Protooncogene homologous to myelocytomatosis virus, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, V-Myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog avian, zc-myc.
|Research Area||Cancer, Cell Cycle, Transcription Factors|
|Pathways||p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus|
Application DetailsProduct Details anti-C-MYC Antibody Target Details C-MYC Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-C-MYC Antibody Target Details C-MYC Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling back to top