anti-Chimpanzee E2F1 antibody for ELISA

Recommended E2F1 Antibody (supplied by: Log in to see )

Antigen
E2F Transcription Factor 1 (E2F1) Antibodies
  • CG6376
  • DRTF1/E2F
  • DmE2F-1
  • Dmel\\CG6376
  • Dp
  • E(Sev-CycE)3A
  • E(var)3-93E
  • E(var)3-95E
  • E(var)93E
  • E2F
  • E2F-1
  • E2F1
  • E2f1
  • Evar(3)164
  • dE2F
  • dE2F1
  • dE2f
  • dE2f1
  • de2f1
  • def21
  • drosE2F1
  • e2f
  • e2f1
  • l(3)07172
  • l(3)j3B1
  • l(3)j3C2
  • l(3)rM729
  • RBAP1
  • RBBP3
  • RBP3
  • mKIAA4009
  • xE2F
  • ATE2FB
  • E2F TRANSCRIPTION FACTOR-1 E2F1
  • E2F transcription factor 1
  • E2FB
  • E2FB TRANSCRIPTION FACTOR
  • E2F transcription factor 1
  • E2F transcription factor 1 L homeolog
  • E2f1
  • E2F1
  • e2f1.L
Epitope
pSer364
44
36
31
28
21
21
17
15
14
14
12
11
11
11
10
9
9
8
8
7
7
5
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chimpanzee, Human
422
124
46
10
8
6
6
5
5
4
3
3
1
1
1
Host
Rabbit
287
123
21
1
Clonality
Polyclonal
Conjugate
This E2F1 antibody is un-conjugated
25
23
20
15
15
13
8
7
5
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
335
180
111
86
79
56
55
42
39
28
9
3
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2470299
$ 550.00
Plus shipping costs $45.00

General

Antigen E2F Transcription Factor 1 (E2F1) Antibodies
Epitope pSer364
(44), (36), (31), (28), (21), (21), (17), (15), (14), (14), (12), (11), (11), (11), (10), (9), (9), (8), (8), (7), (7), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chimpanzee, Human
(422), (124), (46), (10), (8), (6), (6), (5), (5), (4), (3), (3), (1), (1), (1)
Host Rabbit
(287), (123), (21), (1)
Clonality
Polyclonal
Conjugate This E2F1 antibody is un-conjugated
(25), (23), (20), (15), (15), (13), (8), (7), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(335), (180), (111), (86), (79), (56), (55), (42), (39), (28), (9), (3), (2), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-E2F1 Antibody

Target Details E2F1 Application Details Handling Images
Specificity PSer364
Purification Immunoaffinity Chromatography
Immunogen E2F1 antibody was raised against phospho amino acids 360 - 369 of E2F1 (Human).

Target Details E2F1

Product Details anti-E2F1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name E2F1 (E2F1 Antibody Abstract)
Background E2F-1 (also known as tran-scription factor E2F-1, Retinoblastoma binding protein 3, RBBP-3, PRB-binding protein E2F-1, PBR3, Retinoblastoma-associated protein 1 and RBAP-1) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several domains con-served through evolution that are found in most members of the family. These domains include a DNA binding domain, a dimerization domain that determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein as well as E2F2 and E2F3 have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner and mediates both cell proliferation and p53-dependent/independent apoptosis. Increased nuclear expression of this protein has been reported in a variety of cancers.
Gene ID 1869
UniProt Q01094
Research Area Cancer, Transcription Factors
Pathways p53 Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy

Application Details

Product Details anti-E2F1 Antibody Target Details E2F1 Handling Images back to top
Application Notes E2F1 antibody can be used in Western Blot starting at 2 - 4 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation.
Restrictions For Research Use only

Handling

Product Details anti-E2F1 Antibody Target Details E2F1 Application Details Images back to top
Format Liquid
Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store E2F1 antibody at 4 °C or -20 °C.

Images

Product Details anti-E2F1 Antibody Target Details E2F1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody (ABIN2470299) anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody