anti-Human FAS antibody for Dot Blot

Recommended FAS Antibody (supplied by: Log in to see )

Antigen
Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
  • AI196731
  • APO1
  • APT1
  • CD95
  • TNFR6
  • Tnfrsf6
  • lpr
  • TNFRSF6
  • ALPS1A
  • APO-1
  • FAS1
  • FASTM
  • A630082H08Rik
  • FAS
  • Fas (TNF receptor superfamily member 6)
  • Fas (TNF receptor superfamily, member 6)
  • Fas cell surface death receptor
  • fatty acid synthase
  • Fas
  • FAS
  • Fasn
Epitope
pTyr291
48
29
24
18
15
15
15
15
13
12
11
10
9
9
9
8
7
7
6
5
5
5
5
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
647
116
101
21
15
10
6
6
3
3
3
3
2
1
Host
Rabbit
422
304
29
5
4
3
3
Clonality
Polyclonal
Conjugate
This FAS antibody is un-conjugated
73
65
51
29
15
8
8
8
6
6
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Dot Blot (DB)
349
326
211
149
113
86
61
54
52
46
25
17
12
9
7
7
6
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
Options
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Catalog No. ABIN389708
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.92041 ABIN3030905 DB ELISA Rabbit Ig Fraction pTyr291 Log in to see Polyclonal
1 ABIN1953187 DB ELISA WB Alkaline Phosphatase (AP) Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1956491 DB ELISA WB FITC Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1958832 DB ELISA WB PE Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1954059 DB ELISA WB APC Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1955309 DB ELISA WB Biotin Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1957685 DB ELISA WB HRP Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2618796 DB ELISA Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264815 DB ELISA WB Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264817 DB ELISA WB APC Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264746 DB ELISA WB PE Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264819 DB ELISA WB FITC Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264820 DB ELISA WB HRP Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264816 DB ELISA WB Alkaline Phosphatase (AP) Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN2264818 DB ELISA WB Biotin Rabbit IgG pTyr291 Log in to see Polyclonal
1 ABIN1840263 DB Rabbit pTyr291 Log in to see Polyclonal
1 ABIN2794169 DB Rabbit Ig Fraction pTyr291 Log in to see Polyclonal

General

Antigen Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies
Epitope pTyr291
(48), (29), (24), (18), (15), (15), (15), (15), (13), (12), (11), (10), (9), (9), (9), (8), (7), (7), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(647), (116), (101), (21), (15), (10), (6), (6), (3), (3), (3), (3), (2), (1)
Host Rabbit
(422), (304), (29), (5), (4), (3), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This FAS antibody is un-conjugated
(73), (65), (51), (29), (15), (8), (8), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Dot Blot (DB)
(349), (326), (211), (149), (113), (86), (61), (54), (52), (46), (25), (17), (12), (9), (7), (7), (6), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FAS Antibody

Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN389708) Images
Specificity This Phospho-FAS-Y291 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y291 of human FAS.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This FAS Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y291 of human FAS.
Clone RB11173
Isotype Ig

Target Details FAS

Product Details anti-FAS Antibody Application Details Handling References for anti-FAS antibody (ABIN389708) Images back to top
Antigen
Alternative Name FAS (FAS Antibody Abstract)
Background FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.
Synonyms: Tumor necrosis factor receptor superfamily member 6 [Precursor], FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen, CD95 antigen, FAS, APT1, FAS1, TNFRSF6,
Molecular Weight 37732 DA
Gene ID 355
UniProt P25445
Research Area Apoptosis/Necrosis, Cell Signaling, Protein Modifications, Phospho-specific antibodies, Cell Structure
Pathways p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-FAS Antibody Target Details FAS Handling References for anti-FAS antibody (ABIN389708) Images back to top
Application Notes DB = 1:500
Restrictions For Research Use only

Handling

Product Details anti-FAS Antibody Target Details FAS Application Details References for anti-FAS antibody (ABIN389708) Images back to top
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-FAS antibody (ABIN389708)

Product Details anti-FAS Antibody Target Details FAS Application Details Handling Images back to top
Background publications

Delmas, Rébé, Micheau, Athias, Gambert, Grazide, Laurent, Latruffe, Solary: "Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells." in: Oncogene, Vol. 23, Issue 55, pp. 8979-86, 2004

Siegel, Muppidi, Sarker, Lobito, Jen, Martin, Straus, Lenardo: "SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane." in: The Journal of cell biology, Vol. 167, Issue 4, pp. 735-44, 2004

Qiao, Tuohimaa: "Vitamin D3 inhibits fatty acid synthase expression by stimulating the expression of long-chain fatty-acid-CoA ligase 3 in prostate cancer cells." in: FEBS letters, Vol. 577, Issue 3, pp. 451-4, 2004

Images

Product Details anti-FAS Antibody Target Details FAS Application Details Handling References for anti-FAS antibody (ABIN389708) back to top
Supplier Images
Dot Blot (DB) image for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) (pTyr291) antibody (ABIN389708) Dot blot analysis of Phospho-FAS-Y291 polyclonal antibody (ABIN389708) on nitrocellul...