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|Antigen||V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This HRAS antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-HRAS AntibodyTarget Details HRAS Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human H-ras|
Target Details HRASProduct Details anti-HRAS Antibody Application Details Handling Images back to top
|Alternative Name||Hras (HRAS Antibody Abstract)|
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq].
Synonyms: c bas/has, c H ras, c has/bas p21 protein, C K RAS, c K ras2 protein, c Ki ras, c Kirsten ras protein, c ras Ki 2 protein, Cellular c Ki ras2 proto oncogene antibody G1III6 N ras, GTPase HRas, GTPase KRas, GTPase NRas, H Ras 1, H RasIDX, Ha Ras, HRAS 1, HRAS, HRAS1, K Ras 2, K ras, K ras p21 protein, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, Kirsten rat sarcoma 2 viral v Ki ras2 oncogene homolog, KRAS 1, KRAS 2, KRAS, KRAS1, KRAS2, N ras, N ras oncogene, Neuroblastoma RAS viral v ras oncogene homolog, NRAS 1, NRAS, NRAS1, NS3, Oncogene KRAS2, p21ras, PR310 c K ras oncogene antibody RASH 1, RASH1, RASK 2, RASK2, Transforming protein N Ras, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v Ki ras2 Kirsten rat sarcoma viral oncogene homolog, v ras neuroblastoma RAS viral oncogene homolog, RASH_HUMAN.
|Pathways||p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling|
Application DetailsProduct Details anti-HRAS Antibody Target Details HRAS Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-HRAS Antibody Target Details HRAS Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-HRAS Antibody Target Details HRAS Application Details Handling back to top