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Human NFKB1 Protein expressed in Wheat germ - ABIN1312483
Park, Hong, Park, Yoon, Seo, Hyun, Han, Ham, Hwang, Hong: Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression. in Molecular cancer 2015
HMGB1 (show HMGB1 Proteins) mediates fibroblast activity via RAGE (show AGER Proteins)-MAPK (show MAPK1 Proteins) and NF-kappaB signaling in keloid scar formation.
NFkappaB1-94ins/ins (show INS Proteins) genotype was associated with the risk of developing colorectal cancer in Egyptian subjects.
miR (show MLXIP Proteins)-146 exerted protective functions might be via up-regulation of Sirt1 (show SIRT1 Proteins) thereby blocking NF-kappaB and Notch (show NOTCH1 Proteins) pathways.
Data suggest that environmental carcinogen PFOA (perfluorooctanoic acid) stimulates ovarian cancer cell migration, invasion, and MMP2/MMP9 expression by up-regulating ERK/NFkappaB signaling pathway. (MMP = matrix metallopeptidase; NFkappaB = nuclear factor kappa B)
Significantly elevated blood levels of NFkappaB in myelodysplastic syndrome patients.
These data indicate a process of NF-kappaB-induced miR (show MLXIP Proteins)-506 suppression and JAG1 (show JAG1 Proteins) upregulation upon IL-1beta (show IL1B Proteins) induction.
High Expressions of NFkappaB is associated with degenerative knee osteoarthritis.
Inflammatory factors suppress microRNA-1275 transcription in human adipocytes through NF-kappaB.
GSK-3beta is critically important for ordered NF-kappaB signalling through modulation of NEMO (show IKBKG Proteins) phosphorylation.
results establish a role for the linear Ubiquitin coat around cytosolic S. Typhimurium as the local NF-kappaB signalling platform and provide insights into the function of OTULIN in NF-kappaB activation during bacterial pathogenesis
These results indicated that docosahexaenoic acid may attenuate lipopolysaccharide-stimulated inflammatory response in bovine mammary epithelial cells by suppressing NF-kappaB activation through a mechanism partly dependent on PPARgamma (show PPARG Proteins) activation.
Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Proteins) and bFGF (show FGF2 Proteins) expression through the activation of AP-1 (show JUN Proteins) and NF-kappaB in bovine mammary gland fibroblasts.
Data indicate the involvement of PKC-alpha (show PKCa Proteins) in proMMP-2 activation and inhibition of TIMP-2 (show TIMP2 Proteins) expression by NF-kappaB-MT1-MMP (show MMP14 Proteins)-dependent and -independent pathway.
MMP-1 (show MMP1 Proteins) promotes VEGFR2 (show KDR Proteins) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Proteins) and activation of NF-kappaB
dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Proteins) synthesis in the presence of IL-1beta (show IL1B Proteins) and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Proteins) signalling pathways
TRIM5alpha (show TRIM5 Proteins) represses HIV-1 LTR promoter activity by negatively regulating TAK1 (show NR2C2 Proteins)/TAB1 (show TAB1 Proteins)/TAB2 (show TAB2 Proteins)/TAB3 (show TAB3 Proteins)-complex-mediated NF-kappaB activation.
Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.
Porcine parvovirus virus infection significantly induced IL-6 (show IL6 Proteins) expression and this induction depended on NF-kappaB activation and TLR9 (show TLR9 Proteins) signaling pathways in PK-15 cell.
This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB activity and nsp1 was a potent NF-kappaB antagonist for suppression of both interferon (show IFNA Proteins) and early production of pro-inflammatory cytokines.
inhibition of NF-kappaB increases autophagy via JNK (show MAPK8 Proteins) signaling, and promotes steroidogenesis in porcine granulosa cells
SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.
porcine CD74 (show CD74 Proteins) significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 (show CD74 Proteins) may be implicated in the pathogenesis of PCV2 infection.
These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B expression by a PPARgamma (show PPARG Proteins)-dependent pathway in porcine peripheral blood mononuclear cells.
Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-kappaB signaling suppression.
NF-kappaBmiR15abFGF/VEGFA (show VEGFA Proteins) axis contributes to the impaired angiogenic capacity of bone marrowmesenchymal stem cells in high fat dietfed mice.
ESP of fifth-stage larval Angiostrongylus cantonensis stimulates astrocyte activation and IL-1beta (show IL1B Proteins) and IL-6 (show IL6 Proteins) production through NF-kappaB and the Shh (show SHH Proteins) signaling pathway.
Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through NF-kappaB.
By modulating the translation of IkappaBalpha (show NFKBIA Proteins) via the Mnk2 (show MKNK2 Proteins)-eIF4E (show EIF4E Proteins) pathway, Brd4 (show BRD4 Proteins) provides an additional layer of control for NF-kappaB-dependent inflammatory gene expression and inflammatory response.
BCA3 (show AKIP1 Proteins) interacts with Rac1 and augments NF-kappaB signaling in vitro, but has no effect on RANKL (show TNFSF11 Proteins)-induced bone resorption in vivo.
TLR4 (show TLR4 Proteins)-NF-kappaB signaling pathway was involved in the lipopolysaccharide-induced acute lung injury.
This is the first report demonstrating that NF-kappaB signaling may play a key role in compensatory lung growth (CLG (show PLEKHG2 Proteins)). Given its pathway is crucial in tissue regeneration of various organs, NF-kappaB may shed light on identification of molecular triggers or clinically usable key regulators of CLG (show PLEKHG2 Proteins).
Abrogating ClC-3 (show CLCN3 Proteins) blunts lipopolysaccharide-induced Inflammation via blocking the TLR4 (show TLR4 Proteins)/NF-kappaB pathway.
miR-17 approximately 92 family clusters have a role in iNKT cell ontogenesis via modulation of TGF-beta (show TGFB1 Proteins) signaling
Study indicate an essential role of NF-kappaB in gonadal differentiation.
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
DNA binding factor KBF1
, DNA-binding factor KBF1
, nuclear factor NF-kappa-B p105 subunit
, nuclear factor NF-kappa-B p50 subunit
, nuclear factor kappa-B DNA binding subunit
, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
, NF-kB p50 subunit
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
, nuclear factor kappa-B, subunit 1
, nuclear factor of kappa light polypeptide enhancer in B-cells 1
, nuclear factor kappa-B 1
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
, nuclear factor NF-kappa-B p105 subunit-like
, NF kappaB1
, NF-kappa-B1 p84/NF-kappa-B1 p98
, NF-kappaB p50
, nuclear factor kappaB p50
, nuclear factor-kappaB p50
, p50 subunit of NF kappaB
, p50 subunit of NF-kappaB
, BICD-related protein 1
, NF-kB1 precursor protein
, bicaudal D-related protein 1
, coiled-coil domain-containing protein 64A