We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Tumor Protein P53 (TP53) Antibodies|
|Epitope||AA 213-217 Alternatives|
|Reactivity||Chicken, Cow (Bovine), Hamster, Human, Mammalian, Monkey, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This p53 antibody is un-conjugated Alternatives|
Immunoprecipitation (IP), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-p53 AntibodyTarget Details p53 Application Details Handling Images
|Specificity||Recognizes an epitope of p53 between amino acids 156-214 which is present in some malignant tissues but not in normal and pre-malignant tissues. PAb240 is commonly reported as being mutant specific, however there are reports in the literature which suggest that conformational changes in the wild type may result in recognition by this clone.|
|Purification||Protein A purified|
P53-beta-galactosidase fusion protein ( AA 213-217 ).
Type of Immunogen: Fusion protein
Target Details p53Product Details anti-p53 Antibody Application Details Handling Images back to top
|Alternative Name||TP53 / p53 (TP53 Antibody Abstract)|
Name/Gene ID: TP53
Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1
|Pathways||p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy|
Application DetailsProduct Details anti-p53 Antibody Target Details p53 Handling Images back to top
Approved: IP, WB
Usage: Western Blot: Mutant p53 occurs because point mutations cause a conformational disruption. This exposes an internal epitope that LS-C45433 is specific for. To be able to distinguish between wild and mutant forms of p53 non reduced conditions must be used.
|Restrictions||For Research Use only|
HandlingProduct Details anti-p53 Antibody Target Details p53 Application Details Images back to top
|Buffer||PBS, pH 7.4, 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|