anti-Monkey PML antibody for Western Blotting

Recommended PML Antibody (supplied by: Log in to see )

Antigen
Promyelocytic Leukemia (PML) Antibodies
  • MYL
  • PP8675
  • RNF71
  • TRIM19
  • 1200009E24Rik
  • AI661194
  • Trim19
  • RGD1562602
  • PML
  • promyelocytic leukemia
  • PML
  • Pml
Epitope
N-Term
18
15
14
8
7
7
6
5
5
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey
138
43
12
2
2
2
1
1
1
Host
Rabbit
113
41
1
Clonality
Polyclonal
Conjugate
This PML antibody is un-conjugated
7
6
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
135
59
58
45
43
39
17
16
7
6
5
4
3
3
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN1583526
$ 275.00
Plus shipping costs $45.00

General

Antigen Promyelocytic Leukemia (PML) Antibodies
Epitope N-Term
(18), (15), (14), (8), (7), (7), (6), (5), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey
(138), (43), (12), (2), (2), (2), (1), (1), (1)
Host Rabbit
(113), (41), (1)
Clonality
Polyclonal
Conjugate This PML antibody is un-conjugated
(7), (6), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(135), (59), (58), (45), (43), (39), (17), (16), (7), (6), (5), (4), (3), (3), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-PML Antibody

Target Details PML Application Details Handling References for anti-PML antibody (ABIN1583526) Images
Blocking Peptide Blocking peptide for this product available: ABIN1607016
Cross-Reactivity Monkey
Purification Antibody was purified by Protein-G affinity chromatography.
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PML.

Target Details PML

Product Details anti-PML Antibody Application Details Handling References for anti-PML antibody (ABIN1583526) Images back to top
Antigen
Alternative Name PML (PML Antibody Abstract)
Background

Alternate Names: Probable transcription factor PML, Tripartite motif-containing protein 19, RING finger protein 71, PML, MYL, RNF71, TRIM19, Promyelocytic leukemia protein

Description: Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.

NCBI Accession NP_150241
UniProt P29590
Research Area Cancer
Pathways p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Application Details

Product Details anti-PML Antibody Target Details PML Handling References for anti-PML antibody (ABIN1583526) Images back to top
Application Notes E: 1:500-1:1,000, WB: 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-PML Antibody Target Details PML Application Details References for anti-PML antibody (ABIN1583526) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL (1 mg/mL) of PBS pH 7.4 with 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handling Advice Minimize freeze-thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Expiry Date 12 months

References for anti-PML antibody (ABIN1583526)

Product Details anti-PML Antibody Target Details PML Application Details Handling Images back to top
Product cited in:

Kolegraff, Nava, Helms, Parkos, Nusrat: "Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/?-catenin signaling." in: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1121-34, 2011

Schnoor, Betanzos, Weber, Parkos: "Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis." in: Mucosal immunology, Vol. 2, Issue 1, pp. 33-42, 2008