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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN2564364 | EIA IHC ELISA WB | Goat | IgG | Internal Region | Log in to see | Polyclonal | 0 | ||
1 | ABIN5556327 | EIA WB | Rabbit | Ig Fraction | AA 187-216, Middle Region | Log in to see | Polyclonal | 0 | ||
1 | ABIN5553071 | EIA IHC (p) WB | Goat | Internal Region | Log in to see | Polyclonal | 0 | |||
1 | ABIN5609774 | ELISA EIA IHC WB | Biotin | Goat | Internal Region | Log in to see | Polyclonal | 0 | ||
1 | ABIN1108976 | Func EIA WB | Mouse | IgG1 | Log in to see | MA-33H1F7 | 5 | |||
1 | ABIN264029 | EIA | Mouse | IgG | Log in to see | 1-79769313486232E-308 | 0 | |||
1 | ABIN1108977 | Func EIA IHC (fro) WB | Mouse | IgG1 | Log in to see | MA-33H1F7 | 3 | |||
1 | ABIN5539802 | ELISA EIA IHC WB | Biotin | Goat | Internal Region | Log in to see | Polyclonal | 0 | ||
1 | ABIN191654 | EIA IHC (fro) IHC (p) RIA | Goat | Log in to see | Polyclonal | 0 | ||||
1 | ABIN4952039 | ELISA EIA IHC WB | Biotin | Goat | Ig Fraction | Log in to see | Polyclonal | 0 | ||
1 | ABIN4952038 | ELISA EIA IHC WB | Goat | Ig Fraction | Log in to see | Polyclonal | 0 | |||
1 | ABIN1108974 | Func EIA | Mouse | IgG1 | Log in to see | MA-56A7C10 | 2 | |||
1 | ABIN1108975 | Func EIA | Mouse | IgG1 | Log in to see | MA-55F4C12 | 3 | |||
1 | ABIN5541683 | EIA FACS IHC (p) WB | Mouse | IgG1 | Log in to see | 1D5 | 0 | |||
1 | ABIN191652 | EIA IHC (fro) IHC (p) RIA | Goat | Log in to see | Polyclonal | 0 | ||||
1 | ABIN264710 | EIA IHC (fro) WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN613279 | EIA RIA | Biotin | Rabbit | IgG | Log in to see | Polyclonal | 0 | ||
1 | ABIN613753 | EIA RIA | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
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Antigen | serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibodies |
Epitope | Internal Region Alternatives |
Reactivity | Human Alternatives |
Host | Goat Alternatives |
Clonality | |
Conjugate | This SERPINE1 antibody is un-conjugated Alternatives |
Application |
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-SERPINE1 AntibodyTarget Details SERPINE1 Application Details Handling Images |
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Sequence | GFKIDDKGMA PALRH |
Specificity | This antibody detects SERPINE1 / PAI1 (Internal). It is expected to recognise both reported isoforms. |
Cross-Reactivity (Details) |
Species reactivity (expected):Canine (Dog). Species reactivity (tested):Human. |
Purification | Immunoaffinity Chromatography |
Immunogen | Synthetic peptide from internal region of Human PAI1 (NP_000593.1, NP_001158885.1). |
Target Details SERPINE1Product Details anti-SERPINE1 Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | SERPINE1 / PAI1 (SERPINE1 Antibody Abstract) |
Background | PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1 |
Gene ID | 5054 |
NCBI Accession | NP_000593 |
UniProt | P05121 |
Pathways | p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration |
Application DetailsProduct Details anti-SERPINE1 Antibody Target Details SERPINE1 Handling Images back to top |
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Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
HandlingProduct Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Images back to top |
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Concentration | 0.5 mg/mL |
Buffer | Tris saline buffer, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freezing and thawing. |
Storage | 4 °C/-20 °C |
Storage Comment | Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. |
ImagesProduct Details anti-SERPINE1 Antibody Target Details SERPINE1 Application Details Handling back to top |
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Supplier Images |