anti-Human TNFRSF10B antibody for Cytometry by Time of Flight

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Epitope
AA 56-182
46
14
13
12
10
10
9
8
8
8
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
301
69
29
2
1
1
1
1
Host
Mouse
182
147
8
6
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
19
18
16
6
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
198
130
68
61
39
35
30
27
14
13
13
8
3
3
2
2
1
1
Supplier
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Catalog No. ABIN4900599
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4361778 CyTOF FACS WB Mouse IgG1 Extracellular Domain Log in to see DR5-01-1 1

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Epitope AA 56-182
(46), (14), (13), (12), (10), (10), (9), (8), (8), (8), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(301), (69), (29), (2), (1), (1), (1), (1)
Host Mouse
(182), (147), (8), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is un-conjugated
(19), (18), (16), (6), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
(198), (130), (68), (61), (39), (35), (30), (27), (14), (13), (13), (8), (3), (3), (2), (2), (1), (1)
Pubmed 17 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN4900599) Images
Specificity Detects human TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or recombinant mouse TRAIL R2.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Immunogen Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B, Ile56-Glu182, Accession # O14763
Clone 71908
Isotype IgG2b
Plasmids, Primers & others

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN4900599) Images back to top
Antigen
Alternative Name TRAIL R2/TNFRSF10B (TNFRSF10B Antibody Abstract)
Background Alternative Names: CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
Gene ID 8795
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN4900599) Images back to top
Application Notes Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN4900599) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-TNFRSF10B antibody (ABIN4900599)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Product cited in:

Lee, Hyun, Kim, Kang, Kim: "Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL." in: Oncology research, Vol. 24, Issue 6, pp. 495-509, 2017 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Neumann, Hasenauer, Pollak, Scheurich: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." in: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, 2014

Tang, Lu, Tu, Huang, Fu, Cao, Huang, Cheng, Dai, Zhang: "TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells." in: Anticancer research, Vol. 34, Issue 2, pp. 729-34, 2014 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Rat (Rattus)).

Stenqvist, Nagaeva, Baranov, Mincheva-Nilsson: "Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome-mediated immune privilege of the fetus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5515-23, 2013 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Suzuki-Karasaki, Ochiai, Suzuki-Karasaki: "Crosstalk between mitochondrial ROS and depolarization in the potentiation of TRAIL-induced apoptosis in human tumor cells." in: International journal of oncology, Vol. 44, Issue 2, pp. 616-28, 2013 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Zhou, Tian, Long, Quan, Liu, Cao: "Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress." in: PLoS ONE, Vol. 8, Issue 3, pp. e58855, 2013 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Neumann, Bidon, Branschädel, Krippner-Heidenreich, Scheurich, Doszczak: "The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity." in: PLoS ONE, Vol. 7, Issue 8, pp. e42526, 2012 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Moniri, Sun, Rayat, Dai, Ao, He, Verchere, Dai, Warnock: "TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells." in: Cancer gene therapy, Vol. 19, Issue 9, pp. 652-8, 2012 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Stary, Klein, Kohlhofer, Koszik, Scherzer, Müllauer, Quendler, Kohrgruber, Stingl: "Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients." in: Blood, Vol. 114, Issue 18, pp. 3854-63, 2009 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Zauli, Rimondi, Celeghini, Milani, Secchiero: "Dexamethasone counteracts the anti-osteoclastic, but not the anti-leukemic, activity of TNF-related apoptosis inducing ligand (TRAIL)." in: Journal of cellular physiology, Vol. 222, Issue 2, pp. 357-64, 2009 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Barbarotto, Corallini, Rimondi, Fadda, Mischiati, Grill, Vaccarezza, Celeghini: "Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells." in: Journal of cellular biochemistry, Vol. 104, Issue 2, pp. 595-605, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Toscano, Fajoui, Gay, Lalaoui, Parmentier, Chayvialle, Scoazec, Micheau, Abello, Saurin: "P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells." in: Oncogene, Vol. 27, Issue 30, pp. 4161-71, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Weinmann, Wischhusen, Demma, Naumann, Roth, Dasmahapatra, Weller: "A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis." in: Cell death and differentiation, Vol. 15, Issue 4, pp. 718-29, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Seal, Hockenbery, Spaulding, Kiem, Abbassi, Deeg: "Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals." in: Experimental hematology, Vol. 36, Issue 12, pp. 1660-72, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Shankar, Chen, Ganapathy, Singh, Srivastava: "Diallyl trisulfide increases the effectiveness of TRAIL and inhibits prostate cancer growth in an orthotopic model: molecular mechanisms." in: Molecular cancer therapeutics, Vol. 7, Issue 8, pp. 2328-38, 2008 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Dunn, Brunetto, Reynolds, Christophides, Kennedy, Lampertico, Das, Lopes, Borrow, Williams, Humphreys, Afford, Adams, Bertoletti, Maini: "Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 667-80, 2007 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Singh, Shankar, Srivastava: "HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma." in: Oncogene, Vol. 24, Issue 29, pp. 4609-23, 2005 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).