anti-Human TNFRSF10B antibody for Fluorescence Microscopy

Recommended TNFRSF10B Antibody

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Epitope
C-Term
26
14
13
9
9
9
8
8
8
7
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
291
61
30
1
1
1
1
1
Host
Rabbit
186
133
6
2
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
18
15
12
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
178
101
74
58
42
30
29
27
13
13
12
8
3
3
2
2
Options
Catalog No. ABIN6655116
$ 427.90
Plus shipping costs $45.00 and $22.60 dry ice

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Epitope C-Term
(26), (14), (13), (9), (9), (9), (8), (8), (8), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(291), (61), (30), (1), (1), (1), (1), (1)
Host Rabbit
(186), (133), (6), (2), (2)
Clonality
Polyclonal
Conjugate This TNFRSF10B antibody is un-conjugated
(18), (15), (12), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
(178), (101), (74), (58), (42), (30), (29), (27), (13), (13), (12), (8), (3), (3), (2), (2)
Supplier

Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling Images
Purification Anti-DR5 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with DR5 TRAILR2 from Human based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-DR5 TRAILR2 from other sources has not been determined.
Immunogen

Immunogen: DR5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human DR5.

Immunogen Type: Peptide

Isotype IgG
Plasmids, Primers & others

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling Images back to top
Antigen
Alternative Name DR5 (TNFRSF10B Antibody Abstract)
Background

Synonyms: Tumor necrosis factor receptor superfamily member 10B, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, CD_antigen=CD262

Background: DR5 TRAILR2 antibody detects human DR5 TrailR2. Apoptosis induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB. Anti DR5 TRAILR2 is ideal for investigators involved in apoptosis and NF-kappa B research.

Gene Name: TNFRSF10B

Gene ID 8795
NCBI Accession NP_003833
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling Images back to top
Application Notes

Immunohistochemistry Dilution: User Optimized

Application Note: Anti-DR5 Antibody is suitable for use in Flow (Cell Surface) Cytometry, IF/ICC, IHC (paraffin), and WB. Expect a band approximately 47.9 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Flow Cytometry Dilution: User Optimized

Western Blot Dilution: 5 μg/mL

IF Microscopy Dilution: User Optimized

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Images back to top
Format Liquid
Buffer

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage RT,4 °C,-20 °C
Storage Comment Store DR5 antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.