anti-Human TNFRSF10B antibody for Neutralization

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Reactivity
Human
324
77
27
1
1
1
1
1
Host
Mouse
181
168
10
6
6
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is conjugated to Biotin
23
19
16
8
6
5
5
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut)
194
162
73
51
38
32
27
25
16
13
13
4
4
3
3
3
2
1
Options
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Catalog No. ABIN2964487
$ 981.33
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2964485 ICC FACS IP Neut Mouse IgG1 Log in to see HS201
1 ABIN2964486 ICC FACS IP Neut Mouse IgG1 Log in to see HS201

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human
(324), (77), (27), (1), (1), (1), (1), (1)
Host Mouse
(181), (168), (10), (6), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is conjugated to Biotin
(23), (19), (16), (8), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut)
(194), (162), (73), (51), (38), (32), (27), (25), (16), (13), (13), (4), (4), (3), (3), (3), (2), (1)
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling Images
Specificity Reacts with human TRAIL-R2
Cross-Reactivity (Details) Does not cross-react with human TRAIL-R1, -R3 or -R4.
Purification Purified
Immunogen Recombinant human TRAIL-R2 (DR5).
Clone HS201
Isotype IgG1

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling Images back to top
Antigen
Alternative Name TRAIL-R2 (TNFRSF10B Antibody Abstract)
Background TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Gene ID 8795
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling Images back to top
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
B/N: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution)

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS, 0.02 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at +4°C for short term storage or at -20°C for long term storage. Stable for at least 1 year after receipt when stored at -20°C. Avoid repeated freezing and thawing.
Expiry Date 12 months