anti-Mouse (Murine) TNFRSF10B antibody for Immunocytochemistry

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Reactivity
Human, Mouse (Murine)
322
76
27
1
1
1
1
1
Host
Rabbit
178
169
10
6
6
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
23
20
16
8
6
5
5
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
192
163
71
52
38
33
27
23
16
16
13
4
4
3
3
2
1
1
Supplier
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Catalog No. ABIN1002207
$ 511.06
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1173677 ICC IHC WB Rabbit IgG AA 233-367 Log in to see Polyclonal 0
1 ABIN1860800 ICC IHC WB Rabbit IgG AA 54-180 Log in to see Polyclonal 0
1 ABIN213934 ICC IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1030367 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal 2
1 ABIN1733770 ICC IF IHC (p) WB Rabbit IgG AA 388-407 Log in to see Polyclonal 0
1 ABIN4903511 ICC WB Mouse IgG Log in to see 0
1 ABIN1733772 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1583640 ELISA ICC IF WB Rabbit Log in to see Polyclonal 0
1 ABIN4361780 ELISA ICC IF WB Rabbit Log in to see Polyclonal 0
1 ABIN2887551 ICC WB Mouse Log in to see 0
1 ABIN1887405 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1885436 ICC WB Mouse Log in to see 7F4-F8-G11 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Human, Mouse (Murine)
(322), (76), (27), (1), (1), (1), (1), (1)
Host Rabbit
(178), (169), (10), (6), (6), (2)
Clonality
Polyclonal
Conjugate This TNFRSF10B antibody is un-conjugated
(23), (20), (16), (8), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(192), (163), (71), (52), (38), (33), (27), (23), (16), (16), (13), (4), (4), (3), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN1002207) Images
Blocking Peptide Blocking peptide for this product available: ABIN1003787
Purification Affinity chromatography purified via peptide column.
Immunogen Rabbit polyclol DR5 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DR5 precursor .
Isotype IgG

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN1002207) Images back to top
Antigen
Alternative Name Death Receptor 5 (TNFRSF10B Antibody Abstract)
Background Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kappaB.
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN1002207) Images back to top
Application Notes DR5 antibody can be used for detection of DR5 expression by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user.) Antibody can also be used for immunocytochemistry and ELISA and might be suited for other applications not tested so far. Whole cell lysate from HeLa cells can be used as positive control. DR5 antibody is human and mouse reactive and has no cross reaction to DR4.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN1002207) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-TNFRSF10B antibody (ABIN1002207)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Background publications

Walczak, Degli-Esposti, Johnson, Smolak, Waugh, Boiani, Timour, Gerhart, Schooley, Smith, Goodwin, Rauch: "TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL." in: The EMBO journal, Vol. 16, Issue 17, pp. 5386-97, 1997

MacFarlane, Ahmad, Srinivasula, Fernandes-Alnemri, Cohen, Alnemri: "Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL." in: The Journal of biological chemistry, Vol. 272, Issue 41, pp. 25417-20, 1997

Pan, Ni, Wei, Yu, Gentz, Dixit: "An antagonist decoy receptor and a death domain-containing receptor for TRAIL." in: Science (New York, N.Y.), Vol. 277, Issue 5327, pp. 815-8, 1997

Sheridan, Marsters, Pitti, Gurney, Skubatch, Baldwin, Ramakrishnan, Gray, Baker, Wood, Goddard, Godowski, Ashkenazi: "Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors." in: Science (New York, N.Y.), Vol. 277, Issue 5327, pp. 818-21, 1997