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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN2179888 | IF (p) | Cy3 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179891 | IF (p) | Cy7 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179883 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179885 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179884 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179886 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179889 | IF (p) | Cy5 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179890 | IF (p) | Cy5.5 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2179892 | IF (p) | FITC | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN2807311 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN5012107 | IF (p) | Alexa Fluor 750 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 | |
1 | ABIN5012106 | IF (p) | Alexa Fluor 680 | Rabbit | IgG | AA 108-150 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Twist Homolog 1 (Drosophila) (TWIST1) Antibodies |
Epitope | AA 108-150 Alternatives |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This TWIST1 antibody is un-conjugated Alternatives |
Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-TWIST1 AntibodyTarget Details TWIST1 Application Details Handling Images |
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Purification | Purified by Protein A. |
Immunogen | KLH conjugated synthetic peptide derived from human TWIST |
Isotype | IgG |
Plasmids, Primers & others | |
Target Details TWIST1Product Details anti-TWIST1 Antibody Application Details Handling Images back to top |
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Antigen | |
Background |
Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity). Subcellular location: Nucleus Synonyms: CRS, SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38, Twist-related protein 1, Class A basic helix-loop-helix protein 38, H-twist, TWIST1 |
Gene ID | 7291 |
UniProt | Q15672 |
Pathways | p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity |
Application DetailsProduct Details anti-TWIST1 Antibody Target Details TWIST1 Handling Images back to top |
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Application Notes |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
Restrictions | For Research Use only |
HandlingProduct Details anti-TWIST1 Antibody Target Details TWIST1 Application Details Images back to top |
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Format | Liquid |
Concentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Store at -20°C |
Expiry Date | 12 months |
ImagesProduct Details anti-TWIST1 Antibody Target Details TWIST1 Application Details Handling back to top |
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Supplier Images |
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