IL-36gamma (human) Matched Pair Detection Set
-
- Target See all IL1F9 products
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- Reactivity
- Human
- Detection Method
- Colorimetric
- Host
- Mouse
- Method Type
- Sandwich ELISA
- Detection Range
- 3.9 pg/mL - 250 pg/mL
- Minimum Detection Limit
- 3.9 pg/mL
- Application
- ELISA
- Purpose
- IL-36gamma (human) Matched Pair Detection Set
- Sensitivity
- 1 pg/mL
- Characteristics
- Matched Pair Detection Set. Detects human IL-36gamma in cell culture supernatant. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 3.9 to 250pg/mL. Sensitivity: 1pg/mL. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
- Components
- 1 vial standard protein (100ng) (lyophilized) [STD]1 vial coating antibody (120μl) [COAT]1 vial detection antibody (20μl) [DET]1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]
-
- Restrictions
- For Research Use only
-
- Concentration
- Lot specific
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
-
Short Term Storage: -20°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
-
- Target
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- Alternative Name
- IL-36gamma (IL1F9 Products)
- Synonyms
- IL-1F9 Matched Antibody Pair, IL-1H1 Matched Antibody Pair, IL-1RP2 Matched Antibody Pair, IL1E Matched Antibody Pair, IL1F9 Matched Antibody Pair, IL1H1 Matched Antibody Pair, IL1RP2 Matched Antibody Pair, Il36g Matched Antibody Pair, Il1f9 Matched Antibody Pair, RGD1563019 Matched Antibody Pair, IL36G Matched Antibody Pair, interleukin 36 gamma Matched Antibody Pair, interleukin 1 family, member 9 Matched Antibody Pair, interleukin 36, gamma Matched Antibody Pair, interleukin-36 gamma Matched Antibody Pair, IL36G Matched Antibody Pair, Il1f9 Matched Antibody Pair, Il36g Matched Antibody Pair, LOC100065031 Matched Antibody Pair
- Background
-
Alternate Names/Synonyms: Interleukin-36gamma Interleukin-1 Family Member 9, IL-1F9
Product Description: IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
-
