anti-Mouse (Murine) Cathepsin Z antibody for ELISA

Recommended Cathepsin Z Antibody (supplied by: Log in to see )

Antigen
Cathepsin Z (CTSZ) Antibodies
  • wu:fj81f10
  • zgc:103420
  • CTSZ
  • CTSX
  • AI787083
  • AU019819
  • D2Wsu143e
  • CATX
  • CathePsin Z
  • cathepsin Z
  • cathepsin Z S homeolog
  • papain family cysteine protease
  • cpz-1
  • cpz-2
  • CTSZ
  • ctsz
  • ctsz.S
  • TTHERM_00102779
  • NAEGRDRAFT_78125
  • Ctsz
Epitope
AA 1-306
22
15
11
10
8
8
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
106
31
24
3
2
2
1
1
1
1
1
1
Host
Rabbit
66
46
Clonality
Monoclonal
Conjugate
This Cathepsin Z antibody is un-conjugated
6
6
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
87
52
19
13
7
4
4
3
3
1
1
Supplier
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Catalog No. ABIN2000329
$ 273.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2691919 ELISA Rabbit IgG AA 1-306 Log in to see Polyclonal 0
1 ABIN2427909 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6045211 ELISA IHC Rabbit IgG Log in to see Polyclonal 0
1 ABIN6045219 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2421343 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN4368627 IHC ELISA WB Rabbit Log in to see Polyclonal 0
1 ABIN5025986 ELISA WB Rabbit Log in to see Polyclonal 0

General

Antigen Cathepsin Z (CTSZ) Antibodies
Epitope AA 1-306
(22), (15), (11), (10), (8), (8), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(106), (31), (24), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(66), (46)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cathepsin Z antibody is un-conjugated
(6), (6), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA
(87), (52), (19), (13), (7), (4), (4), (3), (3), (1), (1)
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Product Details anti-Cathepsin Z Antibody

Target Details Cathepsin Z Application Details Handling Images
Specificity Mouse CTSZ / CTSX / Cathepsin Z
No cross-reactivity in ELISA with
Human CTSZ
No Cross-Reactivity Human
Characteristics This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CTSZ / CTSX / Cathepsin Z (rM CTSZ / CTSX / Cathepsin Z, ABIN2007305 NP_071720.1, Met 1-Val 306,.
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse CTSZ / CTSX / Cathepsin Z protein (ABIN2007305)
Clone 009
Isotype IgG
Plasmids, Primers & others

Target Details Cathepsin Z

Product Details anti-Cathepsin Z Antibody Application Details Handling Images back to top
Antigen
Alternative Name CTSZ (CTSZ Antibody Abstract)
Background Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from other human cysteine proteases. It has a very short pro-region that shows no similarity to those of other cathepsins and a three-residue insertion motif that forms a characteristic 'mini loop'. Cathepsin Z exhibits mono- and di-peptidase activity at its C-terminus, and in contrast to cathepsin B, it does not act as an endopeptidase. It is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. Cathepsin Z is widely expressed in human tissues, suggesting that this enzyme could be involved in the normal intracellular protein degradation taking place in all cell types. It is capable to cleave regulatory motifs at C-terminus affecting the function of targeted molecules. Cathepsin X may regulate also the maturation of dendritic cells, a process, which is crucial in the initiation of adaptive immunity. Furthermore, higher levels of Cathepsin Z are also found in tumour and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa, especially after infection by Helicobacter pylori. Cathepsin Z is also ubiquitously distributed in cancer cell lines and in primary tumors from different sources, suggesting that this enzyme may participate in tumor progression.
NCBI Accession NP_071720.1
Pathways Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones

Application Details

Product Details anti-Cathepsin Z Antibody Target Details Cathepsin Z Handling Images back to top
Application Notes ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse CTSZ. The detection limit for Mouse CTSZ is approximately 0.00975 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-Cathepsin Z Antibody Target Details Cathepsin Z Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months