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POMC Proteins

(Proopiomelanocortin (POMC))

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

recommended

POMC Protein (AA 205-267) (GST tag) (ABIN1315730)

POMC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

POMC Protein (AA 27-267) (His tag) (ABIN7124601)

POMC Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

POMC Protein (AA 27-267) (His-IF2DI Tag) (ABIN7124600)

POMC Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA

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POMC Proteins by Origin

Find POMC Proteins for a variety of species such as anti-Human POMC, anti-Rat POMC, anti-Acipenser transmontanus POMC. The species listed below are among those available. Click on a link to go to the corresponding products.

POMC Proteins by Source

Here you will find POMC Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

POMC Proteins by Protein Type

Here you can find POMC Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

POMC Proteins by Application

Find POMC Proteins validated for a specific application such as ELISA, WB, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular POMC Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

POMC Protein (AA 205-267) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1315730

Quantity 10 μg

Datasheet Datasheet

POMC Protein (AA 27-267) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7124601

Quantity 50 μg

Datasheet Datasheet

POMC Protein (AA 27-267) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7124600

Quantity 50 μg

Datasheet Datasheet

POMC Protein (AA 1-267) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1315729

Quantity 25 μg

Datasheet Datasheet

POMC Protein (AA 27-235) (His tag,GST tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7405103

Quantity 100 μg

Datasheet Datasheet

POMC Protein (AA 27-235) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7393751

Quantity 100 μg

Datasheet Datasheet

POMC Protein (AA 23-267) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7415977

Quantity 100 μg

Datasheet Datasheet

POMC Protein

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3011313

Quantity 100 μg

Datasheet Datasheet

POMC Protein (AA 98-138) (His tag)

Reactivity Oncorhynchus keta

Source Yeast

Validations

Cat. No. ABIN1659952

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 1-52) (His tag)

Reactivity Sheep

Source Yeast

Validations

Cat. No. ABIN1667026

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 27-97) (His tag)

Reactivity Guinea Pig

Source Yeast

Validations

Cat. No. ABIN1661110

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 27-99) (His tag)

Reactivity Macaca nemestrina

Source Yeast

Validations

Cat. No. ABIN1666425

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 27-100) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1666424

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 26-101) (His tag)

Reactivity Frog

Source Yeast

Validations

Cat. No. ABIN1663113

Quantity 1 mg

Datasheet Datasheet

POMC Protein (AA 27-103) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1667025

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our POMC Proteins

La Rosa, Uccella, Dainese, Marchet, Placidi, Vigetti, Capella: "Characterization of c-kit (CD117) expression in human normal pituitary cells and pituitary adenomas." in: Endocrine pathology, Vol. 19, Issue 2, pp. 104-11, (2008) (PubMed).

Aliases for POMC Proteins

proopiomelanocortin a (pomca) Proteins
pro-opiomelanocortin-alpha (Pomc) Proteins
proopiomelanocortin (POMC) Proteins
proopiomelanocortin (Pomc) Proteins
ACTH Proteins
alpha-MSH Proteins
alphaMSH Proteins
BE Proteins
Beta-LPH Proteins
beta-MSH Proteins
Clip Proteins
CLIP Proteins
Gamma-LPH Proteins
gamma-MSH Proteins
LPH Proteins
MSH Proteins
Npp Proteins
NPP Proteins
POC Proteins
pomc Proteins
Pomc-1 Proteins
Pomc1 Proteins
Pomc2 Proteins
SI:bZ36D5.1 Proteins
si:bz36d5.2 Proteins
SI:bZ36D5.4 Proteins

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POMC Proteins by Origin

POMC Proteins by Source

POMC Proteins by Protein Type

POMC Proteins by Application

Popular POMC Proteins

Latest Publications for our POMC Proteins

Aliases for POMC Proteins

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