anti-Human Syntaxin 1A (Brain) antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Syntaxin 1A (Brain) Antibody (supplied by: Log in to see )

Antigen
Syntaxin 1A (Brain) (STX1A) Antibodies
  • HPC-1
  • P35-1
  • STX1
  • SYN1A
  • STX1A
  • hpc-1
  • p35-1
  • stx1
  • sx1a
  • syntaxin1a
  • CG10716
  • CG18615
  • CG31136
  • CG5448
  • CT30033
  • Dm Syx1
  • DmSyx1A
  • Dmel\\CG31136
  • SYX1A
  • Syt1A
  • Syx
  • Syx-1A
  • Syx1
  • Syx1a
  • SyxA
  • anon-EST:Gibbs4
  • anon-WO02059370.54
  • dSyx1
  • l(3)06737
  • synt
  • syt-1A
  • syx
  • syx-1
  • syx-1A
  • syx1
  • syx1A
  • syntaxin 1A
  • syntaxin 1A (brain)
  • Syntaxin 1A
  • syntaxin-1A
  • STX1A
  • Stx1a
  • stx1a
  • Syx1A
  • EDI_005240
  • Tsp_07354
Epitope
AA 36-65, N-Term
30
15
14
11
10
7
7
4
4
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
125
76
71
18
14
7
4
4
3
3
2
2
2
2
1
1
1
1
1
Host
Rabbit
112
17
6
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
109
50
49
21
19
18
14
14
7
7
1
1
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Catalog No. ABIN955037
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.954848 ABIN1714932 IF (p) IHC (p) WB Rabbit IgG pSer188 Log in to see Polyclonal 0
9.954848 ABIN752713 IF (p) IHC (p) WB Rabbit IgG AA 1-42, pSer14 Log in to see Polyclonal 0
9.954848 ABIN5079952 IHC (p) Rabbit IgG Log in to see Polyclonal 0
1 ABIN492371 IHC (p) IP WB Mouse IgG1 Log in to see HPC-1 5
1 ABIN1049369 IHC IHC (p) Rabbit N-Term Log in to see Polyclonal 0
1 ABIN1049370 IHC IHC (p) Rabbit Internal Region Log in to see Polyclonal 0
1 ABIN653770 FACS IHC (p) WB Rabbit Ig Fraction AA 29-57, N-Term Log in to see Polyclonal 0
1 ABIN948510 IHC (p) WB Mouse AA 1-251, full length Log in to see Polyclonal 0
1 ABIN5537575 FACS IHC (p) WB Rabbit Ig Fraction AA 29-57, N-Term Log in to see Polyclonal 0
1 ABIN1712447 IHC (p) WB HRP Rabbit IgG pSer188 Log in to see Polyclonal 0
1 ABIN1739753 IHC (p) Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1739754 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN520584 IHC (p) WB Mouse AA 1-251, full length Log in to see Polyclonal 0
1 ABIN1701430 IHC (p) WB Biotin Rabbit IgG pSer188 Log in to see Polyclonal 0
1 ABIN2884395 ELISA IF IHC IHC (p) WB Rabbit IgG AA 1-50 Log in to see Polyclonal 0
1 ABIN5588968 IHC (p) Rabbit Log in to see Polyclonal 0
1 ABIN5588969 IHC (p) Rabbit Log in to see Polyclonal 0
1 ABIN1809661 FACS IHC IHC (p) WB Rabbit AA 29-57 Log in to see Polyclonal 0
1 ABIN1818299 IHC IHC (p) IP WB Mouse IgG1 Log in to see HPC-1 0
1 ABIN2766289 IHC (p) Rabbit N-Term Log in to see Polyclonal 0

General

Antigen Syntaxin 1A (Brain) (STX1A) Antibodies
Epitope AA 36-65, N-Term
(30), (15), (14), (11), (10), (7), (7), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(125), (76), (71), (18), (14), (7), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(112), (17), (6), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(109), (50), (49), (21), (19), (18), (14), (14), (7), (7), (1), (1)
Pubmed 6 references available
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Product details

Target Details Application Details Handling References Images
Specificity This antibody recognizes Human Syntaxin 1A / STX1A (N-term).
Purification Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of Human STX1A Genename: STX1A
Isotype Ig Fraction

Target Details

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Antigen
Alternative Name Syntaxin 1A / STX1A (STX1A Antibody Abstract)
Background This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.Synonyms: Neuron-specific antigen HPC-1, STX1, Syntaxin-1A
Molecular Weight 33023 Da
Gene ID 6804
NCBI Accession NP_001159375
Pathways Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References

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Background publications

Hamdan, Piton, Gauthier, Lortie, Dubeau, Dobrzeniecka, Spiegelman, Noreau, Pellerin, Côté, Henrion, Fombonne, Mottron, Marineau, Drapeau, Lafrenière, Lacaille, Rouleau, Michaud: "De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy." in: Annals of neurology, Vol. 65, Issue 6, pp. 748-53, 2009

Corominas, Ribasés, Cuenca-León, Narberhaus, Serra, del Toro, Roig, Fernández-Fernández, Macaya, Cormand: "Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population." in: Neuroscience letters, Vol. 455, Issue 2, pp. 105-9, 2009

Chen, Nelson, Khauv, Bennett, Radisky, Hirai, Bissell, Radisky: "Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis." in: The Journal of biological chemistry, Vol. 284, Issue 11, pp. 6877-84, 2009

Ramakrishnan, Drescher, Drescher: "Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3." in: The Journal of biological chemistry, Vol. 284, Issue 3, pp. 1364-72, 2009

Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nishigaki, Nozawa, Yamada: "Association of genetic variants with chronic kidney disease in individuals with different lipid profiles." in: International journal of molecular medicine, Vol. 24, Issue 2, pp. 233-46, 2009

Tian, Das, Sheng: "Ca2+-dependent phosphorylation of syntaxin-1A by the death-associated protein (DAP) kinase regulates its interaction with Munc18." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 26265-74, 2003

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Flow cytometric analysis of 293 cells using Syntaxin 1A / STX1A Antibody (N-term) Cat...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Formalin fixed, paraffin embedded skeletal muscle stained with Syntaxin 1A / STX1A An...
Western Blotting (WB) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Western blot analysis of Syntaxin 1A / STX1A Antibody (N-term) in 293 cell line lysat...