ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide
AGTPBP1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN1541167
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for ATP/GTP Binding Protein 1 (AGTPBP1) (C-Term) Peptide (ABIN1541167)
Target
AGTPBP1
(ATP/GTP Binding Protein 1 (AGTPBP1))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequence
- GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-Agtpbp1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))
-
Background
-
Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
Protein Size: 1160 -
Molecular Weight
- 128 kDa
-
Gene ID
- 67269
-
NCBI Accession
- NM_023328, NP_075817
Target
-
You are here:
