Nuclear Protein Localization 4 Homolog (NPLOC4) (N-Term) Peptide
NPLOC4
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all NPLOC4 products
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
- Protein Region
- N-Term
- Origin
- Human, Mouse
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GLKAFGAPNV VEDEIDQYLS KQDGKIYRSR DPQLCRHGPL GKCVHCVPLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Nploc4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
- Synonyms
- NPL4 Peptide, AK129375 Peptide, Npl4 Peptide, mKIAA1499 Peptide, NPL4 homolog, ubiquitin recognition factor Peptide, NPLOC4 Peptide, Nploc4 Peptide
- Background
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The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.
Alias Symbols: AK129375, Npl4, mKIAA1499
Protein Size: 608 - Molecular Weight
- 66 kDa
- Gene ID
- 217365
- NCBI Accession
- NM_001195023, NP_001181952
- UniProt
- P60670
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