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Ataxin 7-Like 3 (ATXN7L3) (Middle Region) Peptide

ATXN7L3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN1541657
  • Target See all ATXN7L3 products
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ATXN7L3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    Synonyms
    E030022H21Rik Peptide, si:busm1-180g5.4 Peptide, si:dz180g5.4 Peptide, wu:fj12f07 Peptide, zgc:136438 Peptide, zgc:158566 Peptide, ataxin 7 like 3 Peptide, ataxin 7-like 3 Peptide, ATXN7L3 Peptide, Atxn7l3 Peptide, atxn7l3 Peptide
    Background
    ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

    Alias Symbols: DKFZp761G2113

    Protein Size: 354
    Molecular Weight
    38 kDa
    Gene ID
    56970
    NCBI Accession
    NM_020218, NP_064603
    UniProt
    Q14CW9
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