Anaphase Promoting Complex Subunit 15 (ANAPC15) (N-Term) Peptide
ANAPC15
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ANAPC15 products
- ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEEDDEDDED
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANAPC15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))
- Synonyms
- APC15 Peptide, C11orf51 Peptide, C15H11orf51 Peptide, anaphase promoting complex subunit 15 Peptide, ANAPC15 Peptide
- Background
-
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Alias Symbols: APC15, C11orf51
Protein Size: 121 - Molecular Weight
- 13 kDa
- Gene ID
- 25906
- NCBI Accession
- NM_014042, NP_054761
- UniProt
- P60006
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