Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) (N-Term) Peptide
EFTUD1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EFTUD1 products
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KVLEERAERE TESQVNPNSE QGEQVYDWST GLEDTDDSHL YFSPEQGNVV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EFTUD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
- Synonyms
- FAM42A Peptide, HsT19294 Peptide, RIA1 Peptide, 4932434J20Rik Peptide, 6030468D11Rik Peptide, AI451340 Peptide, AU019507 Peptide, AU022896 Peptide, D7Ertd791e Peptide, elongation factor like GTPase 1 Peptide, elongation factor like GPTase 1 Peptide, EFL1 Peptide, Efl1 Peptide
- Background
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EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Alias Symbols: FAM42A, HsT19294, RIA1
Protein Interaction Partner: UBC
Protein Size: 1069 - Molecular Weight
- 117 kDa
- Gene ID
- 79631
- NCBI Accession
- NM_001040610, NP_001035700
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