Paternally Expressed 10 (PEG10) (N-Term) Peptide
PEG10
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PEG10 products
- PEG10 (Paternally Expressed 10 (PEG10))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SMMTGRAARW ASAKLERSHY LMHNYPAFMM EMKHVFEDPQ RREVAKRKIR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PEG10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PEG10 (Paternally Expressed 10 (PEG10))
- Synonyms
- EDR Peptide, HB-1 Peptide, MEF3L Peptide, Mar2 Peptide, Mart2 Peptide, RGAG3 Peptide, AA407948 Peptide, Edr Peptide, MyEF-3 Peptide, paternally expressed 10 Peptide, PEG10 Peptide, Peg10 Peptide
- Background
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This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.
Alias Symbols: EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Protein Size: 708 - Molecular Weight
- 80 kDa
- Gene ID
- 23089
- NCBI Accession
- NM_015068, NP_055883
- UniProt
- Q86TG7
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