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SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B) (N-Term) Peptide

SLX1B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2185338
  • Target See all SLX1A/GIYD2 (SLX1B) products
    SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    FFGVYLLYCL NPRYRGRVYV GFTVNTARRV QQHNGGRKKG GAWRTSGRGP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SLX1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))
    Synonyms
    1110030E23Rik Peptide, 2410170E21Rik Peptide, 4833422P03Rik Peptide, AI853643 Peptide, Giyd1 Peptide, Giyd2 Peptide, LRRGT00058 Peptide, RGD1311568 Peptide, GIYD2 Peptide, SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) Peptide, SLX1 homolog B, structure-specific endonuclease subunit Peptide, Slx1b Peptide, SLX1B Peptide
    Background
    This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication, this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.

    Protein Size: 275
    Molecular Weight
    30 kDa
    Gene ID
    79008
    UniProt
    Q9BQ83
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