Syntide-2 Peptide

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Purity > 95 %
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Background The native peptide PLARTLSVAGLPGKK is a selective substrate for CaM kinase II and PKC. It is also a poor substrate for phosphorylase kinase and is not phosphorylated by myosin light chain kinase. The sequence of PLARTLSVAGLPGKK is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the peptide for different kinases are 100 for CaMK II, 22 for PKC, 2 for phosphorylase kinase, and 0.5 for myosin light chain kinase, respectively.
CAS-No 108334-68-5
Restrictions For Research Use only
Storage -20 °C
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 image for Syntide-2 peptide (ABIN399830) Syntide-2 peptide
Product cited in: Barcomb, Coultrap, Bayer: "Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B." in: Molecular pharmacology, Vol. 84, Issue 6, pp. 834-43, 2013 (PubMed).