Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) (N-Term) Peptide
CYP3A4
Reactivity: Human
Host: Synthetic
WB
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- Target See all CYP3A4 products
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- LFKKLGIPGP TPLPFLGNIL SYHKGFCMFD MECHKKYGKV WGFYDGQQPV
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Synonyms
- CP33 Peptide, CP34 Peptide, CYP3A Peptide, CYP3A3 Peptide, CYPIIIA3 Peptide, CYPIIIA4 Peptide, HLP Peptide, NF-25 Peptide, P450C3 Peptide, P450PCN1 Peptide, MGC108372 Peptide, CYP3A80 Peptide, CYP3A4 Peptide, CYP3A21 Peptide, CYPIIIA21 Peptide, CYP3A12 Peptide, cytochrome P450 family 3 subfamily A member 4 Peptide, cytochrome P450 family 3 subfamily A member 43 Peptide, cytochrome P450 3A4 Peptide, cytochrome P450, subfamily IIIA, polypeptide 4 Peptide, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 Peptide, cytochrome P450, family 3, subfamily A, polypeptide 4 Peptide, CYP3A4 Peptide, CYP3A43 Peptide, PTRG_01782 Peptide, PTRG_06060 Peptide, cyp3a4 Peptide
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1,
Protein Size: 167 - Gene ID
- 1576
- NCBI Accession
- NM_001202855, NP_001189784
- UniProt
- P08684
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