Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) (N-Term) Peptide

Details for Product No. ABIN690218, Supplier: Log in to see
Protein Name
  • PAR-3
  • PAR3
  • par3
  • F730031A08
  • f2rl2
  • coagulation factor II thrombin receptor like 2
  • coagulation factor II (thrombin) receptor-like 2
  • coagulation factor II (thrombin) receptor-like 2 L homeolog
  • F2RL2
  • f2rl2
  • F2rl2
  • f2rl2.L
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Options
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Protein Name
Background Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Wysoczynski, Liu, Kucia, Drukala, Ratajczak: "Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling." in: Molecular cancer research : MCR, Vol. 8, Issue 5, pp. 677-90, 2010 (PubMed).