SMT3 Suppressor of Mif Two 3 Homolog 2 (S. Cerevisiae) (SUMO2) (C-Term) Peptide

Details for Product No. ABIN690785, Supplier: Log in to see
Protein Name
  • HSMT3
  • SMT3B
  • SMT3H2
  • SUMO3
  • Smt3A
  • Smt3h2
  • sumo2
  • zgc:92241
  • SUMO2
  • SUMO-2
  • Smt3b
  • hsmt3
  • smt3b
  • smt3h2
  • sumo-2
  • PSMT3
  • ATSUMO2
  • MCO15.11
  • MCO15_11
  • SMALL UBIQUITIN-LIKE MODIFIER 2
  • SUM2
  • SUMO 2
  • small ubiquitin-like modifier 2
  • Smt3B
  • small ubiquitin-like modifier 2
  • small ubiquitin-like modifier 2b
  • small ubiquitin-related modifier 2
  • small ubiquitin-like modifier 2 S homeolog
  • small ubiquitin-like modifier 2 L homeolog
  • SUMO2
  • Sumo2
  • sumo2b
  • LOC714892
  • sumo2.S
  • sumo2.L
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Options
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Specificity The synthetic peptide sequence used to generate the antibody AP1285b was selected from the C-term region of human Xenopus SUMO2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Protein Name
Background SUMO2 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. SUMO2 does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. This protein plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS isoforms 1-4.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Yeh, Gong, Kamitani: "Ubiquitin-like proteins: new wines in new bottles." in: Gene, Vol. 248, Issue 1-2, pp. 1-14, 2000 (PubMed).

Keane, Ettenberg, Nau, Banerjee, Cuello, Penninger, Lipkowitz: "cbl-3: a new mammalian cbl family protein." in: Oncogene, Vol. 18, Issue 22, pp. 3365-75, 1999 (PubMed).