N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1) (Center) Peptide

Details for Product No. ABIN691096, Supplier: Log in to see
Protein Name
  • AAC1
  • MNAT
  • NAT-1
  • NATI
  • Nat-1
  • Nat
  • NAT1
  • AT-I
  • N-acetyltransferase 1
  • N-acetyl transferase 1
  • N-acetyltransferase 1 (arylamine N-acetyltransferase)
  • arylamine N-acetyltransferase 1-like
  • NAT1
  • Nat1
  • LOC101095575
Protein Region
Center
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP13168c was selected from the center region of NAT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Protein Name
Background This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Barker, Husain, Neale, Martini, Zhang, Doll, States, Hein: "Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1." in: Pharmacogenetics and genomics, Vol. 16, Issue 7, pp. 515-25, 2006 (PubMed).

Boukouvala, Sim: "Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts." in: Basic & clinical pharmacology & toxicology, Vol. 96, Issue 5, pp. 343-51, 2005 (PubMed).