Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) (Center) Peptide

Details for Product No. ABIN691161, Supplier: Log in to see
Protein Name
  • zgc:92200
  • wu:fa04c03
  • wu:fj80b06
  • wu:fj80h04
  • ACAS2
  • ACECS
  • ACS
  • ACSA
  • dJ1161H23.1
  • 1110017C11Rik
  • ACAS
  • Acas1
  • Acas2
  • AceCS1
  • Acs1
  • acyl-CoA synthetase short chain family member 2
  • acetyl-coenzyme A synthetase, cytoplasmic
  • acyl-CoA synthetase short-chain family member 2
  • acyl-CoA synthetase short chain family member 1
  • ACSS2
  • LOC100179555
  • LOC100211402
  • acss2
  • ACSS1
  • Acss2
Protein Region
Center
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP13231c was selected from the Center region of ACSS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Protein Name
Background This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).