Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 530-826) Peptide
HIF1A
Reactivity: Human
Host: Escherichia coli (E. coli)
SDS
Dithiothreitol (DTT)
1 image
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- Target See all HIF1A products
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- Peptide Type
- Recombinant
- Protein Region
- AA 530-826
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MEFKLELVEK LFAEDTEAKN PFSTQDTDLD LEMLAPYIPM DDDFQLRSFD QLSPLESSSA SPESASPQST VTVFQQTQIQ EPTANATTTT ATTDELKTVT KDRMEDIKIL IASPSPTHIH KETTSATSSP YRDTQSRTAS PNRAGKGVIE QTEKSHPRSP NVLSVALSQR TTVPEEELNP KILALQNAQR KRKMEHDGSL FQAVGIGTLL QQPDDHAATT SLSWKRVKGC KSSEQNGMEQ KTIILIPSDL ACRLLGQSMD ESGLPQLTSY DCEVNAPIQG SRNLLQGEEL LRALDQVN
- Characteristics
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Purified recombinant Human Hif1 a? protein
Expression System: E.coli
The recombinant protein appeared as a 40 kDa band on SDS-PAGE. - Purity
- > 95 % pure
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- Application Notes
- Hif1-alpha protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH7.5, containing 0 mM DTT.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- Synonyms
- hif1a Peptide, AA959795 Peptide, HIF1alpha Peptide, MOP1 Peptide, bHLHe78 Peptide, HIF-1A Peptide, HIF-1alpha Peptide, HIF1 Peptide, HIF1-ALPHA Peptide, PASD8 Peptide, HIF1-alpha Peptide, hif-1a Peptide, hypoxia inducible factor 1 alpha Peptide, hypoxia inducible factor 1, alpha subunit Peptide, hypoxia inducible factor 1 alpha subunit Peptide, HIF (Hypoxia Inducible Factor) homologa Peptide, hif-1a Peptide, Hif1a Peptide, HIF1A Peptide, hif1a Peptide, hif-1 Peptide
- Background
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Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1 beta subunit and one of three subunits (Hif-1alpha, Hif-2alpha or Hif-3alpha). The activation of Hif-1 alpha is closely associated with a variety of tumors and oncogenic pathways. Hif-1 alpha consists of DNA binding domain (DBD domain), Dimerization domain and C-terminal regulatiory domains, including two transactivation domains (TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains. Hif-1 alpha (530-826 residues) contains two TAD and inhibitory domain. Recombinant Hif-1 alpha (530-826 residues) was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Hifa-1 protein, Hif1a, HIF 1A protein, Hifa 1 protein, ARNT interacting protein protein, MOP1 protein, HIF 1alpha protein, bHLHe78 protein, Hif-1 alpha (530-826 aa) protein, HIF-1 alpha protein, Member of PAS protein 1 protein, Hifa-1, Hypoxia-inducible factor-1a Basic helix loop helix PAS protein MOP1 protein, MOP 1 protein, Member of the PAS Superfamily 1 protein, PASD8 protein, Hypoxia inducible factor 1 alpha isoform I.3 protein, Basic-helix-loop-helix-PAS protein MOP1 protein, Hypoxia-inducible factor 1 alpha protein, HIF1A protein, HIF1 alpha protein, PASD 8 protein, , Member of PAS protein 1 protein, Member of PAS superfamily 1 protein, Hifa 1, ARNT-interacting protein protein, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor protein, Hypoxia inducible factor 1 alpha subunit protein, HIF1 A protein, Hypoxia inducible factor 1 alpha protein - Molecular Weight
- 32.8 kDa (298 AA)
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