Abl-Interactor 1 (ABI1) (N-Term) Peptide
ABI1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ABI1 products
- ABI1 (Abl-Interactor 1 (ABI1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- HKIIAPANME RPVRYIRKPI DYTVLDDVGH GVKWLKAKHG NNQPARTGTL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ABI1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ABI1 (Abl-Interactor 1 (ABI1))
- Synonyms
- ABI-1 Peptide, ABLBP4 Peptide, E3B1 Peptide, NAP1BP Peptide, SSH3BP Peptide, SSH3BP1 Peptide, NAP1 Peptide, Ssh3bp1 Peptide, E3b1 Peptide, abi1 Peptide, wu:fc66g09 Peptide, wu:fk56a10 Peptide, zgc:73174 Peptide, MGC84356 Peptide, ABI1 Peptide, abi-1 Peptide, e3b1 Peptide, nap1bp Peptide, ssh3bp Peptide, ssh3bp1 Peptide, wu:fe48a10 Peptide, zgc:153534 Peptide, DKFZp469P1319 Peptide, abl interactor 1 Peptide, abl-interactor 1 Peptide, abl-interactor 1a Peptide, abl interactor 1 S homeolog Peptide, abl-interactor 1b Peptide, Abl-interactor 1 Peptide, Abl interactor 1 Peptide, ABI1 Peptide, Abi1 Peptide, abi1a Peptide, abi1.S Peptide, abi1 Peptide, abi1b Peptide, Bm1_44660 Peptide, LOAG_04356 Peptide
- Background
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This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
Alias Symbols: ABI-1, E3B1, NAP1BP, SSH3BP, SSH3BP1, ABLBP4
Protein Interaction Partner: NCF1C,ABL1,NCKAP1,DNM2,ABI1,ABL1,CYFIP2,ENAH,EPS8,EPS8L1,EVL,HSPA8,MINK1,NCF1,NCK1,NCK2,NCKAP1,NEB,NIN,PAK2,SOS1,SOS2,SPTA1,SPTAN1,VASP,WASF1,WASF2,ABL1,APBB1,ENAH,EPS8,EPS8L1,EPS8L2,EPS8L3,GAS7,NCK1,NCKAP1,PRPF40A,RYK,SOS1,TCERG1
Protein Size: 508 - Molecular Weight
- 56 kDa
- Gene ID
- 10006
- NCBI Accession
- NM_005470, NP_005461
- UniProt
- Q8IZP0
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