Adrenocortical Dysplasia Homolog (ACD) Peptide
ACD
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACD products
- ACD (Adrenocortical Dysplasia Homolog (ACD))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACD antibody (Catalog #: ARP58254_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACD (Adrenocortical Dysplasia Homolog (ACD))
- Synonyms
- PIP1 Peptide, PTOP Peptide, TINT1 Peptide, TPP1 Peptide, ACD Peptide, ACD, shelterin complex subunit and telomerase recruitment factor Peptide, adrenocortical dysplasia Peptide, ACD Peptide, Acd Peptide
- Background
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ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Alias Symbols: PIP1, PTOP, TINT1, TPP1
Protein Interaction Partner: POT1,TINF2,LLGL1,POT1,TINF2,USP7,XRCC6,POT1,TERF1,TINF2,XRCC6
Protein Size: 544 - Molecular Weight
- 58 kDa
- Gene ID
- 65057
- NCBI Accession
- NM_001082486, NP_001075955
- UniProt
- Q96AP0
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