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ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) (N-Term) Peptide

ADAMTS18 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972910
  • Target See all ADAMTS18 products
    ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ADAMTS18 antibody (Catalog #: ARP53478_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))
    Synonyms
    9630038L21 Peptide, ADAMTS21 Peptide, E130314N14Rik Peptide, KNO2 Peptide, RGD1560118 Peptide, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 Peptide, ADAM metallopeptidase with thrombospondin type 1 motif 18 Peptide, ADAM metallopeptidase with thrombospondin type 1 motif, 18 Peptide, Adamts18 Peptide, ADAMTS18 Peptide
    Background
    ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

    Alias Symbols: ADAMTS21, KNO2

    Protein Size: 1221
    Molecular Weight
    104 kDa
    Gene ID
    170692
    NCBI Accession
    NM_199355, NP_955387
    UniProt
    Q8TE60
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