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Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (Middle Region) Peptide

AIFM1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973027
  • Target See all AIF (AIFM1) products
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AIFM1 antibody (Catalog #: AVARP02013_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Synonyms
    AIF Peptide, CMTX4 Peptide, COWCK Peptide, COXPD6 Peptide, PDCD8 Peptide, CG7263 Peptide, DmAIF Peptide, Dmel\\CG7263 Peptide, GB16024 Peptide, DDBDRAFT_0187853 Peptide, DDBDRAFT_0191137 Peptide, DDB_0187853 Peptide, DDB_0191137 Peptide, aif Peptide, pdcd8 Peptide, AIFM1 Peptide, PCD8 Peptide, AIFsh2 Peptide, Hq Peptide, Pdcd8 Peptide, mAIF Peptide, Aif Peptide, zgc:91994 Peptide, apoptosis inducing factor mitochondria associated 1 Peptide, allograft inflammatory factor 1 Peptide, Apoptosis inducing factor Peptide, apoptosis-inducing factor 1, mitochondrial Peptide, apoptosis inducing factor Peptide, apoptosis inducing factor, mitochondria associated 1 Peptide, apoptosis-inducing factor, mitochondrion-associated, 1 Peptide, apoptosis-inducing factor, mitochondrion-associated 1 Peptide, AIFM1 Peptide, AIF1 Peptide, AIF Peptide, LOC412212 Peptide, aif Peptide, aifm1 Peptide, Aifm1 Peptide
    Background
    AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.

    Alias Symbols: AIF, MGC111425, PDCD8, COXPD6

    Protein Interaction Partner: C4orf14,CASP3,EIF3G,HSPA1A,HSPA1B,SETDB1,STC2,TSC22D4,WWC1,BRF2,C20orf24,HSPA1A,MLF2,MLH1,PELO,PMS2,PTP4A3,SETDB1,STC2,UBC,XIAP

    Protein Size: 613
    Molecular Weight
    67 kDa
    Gene ID
    9131
    NCBI Accession
    NM_004208, NP_004199
    UniProt
    O95831
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