BCL2-Associated X Protein (BAX) (N-Term) Peptide

Details for Product No. ABIN973744, Supplier: Log in to see
Protein Name
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Protein Region
N-Term
Origin
Human
11
9
7
6
6
2
2
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-BAX antibody (BCL2-Associated X Protein) (N-Term) (ABIN2787858)
Sequence IMKTGALLLQ GFIQDRAGRM GGEAPELALD PVPQDASTKK LSECLKRIGD
Characteristics This is a synthetic peptide designed for use in combination with anti-BAX Antibody(ARP58870_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Protein Name BCL2-Associated X Protein (BAX)
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Alias Symbols: BCL2L4

Protein Interaction Partner: TP53,TP53,TP73,BBC3,BCL2,BCL2,BCL2L1,BCL2L1,BID,MOAP1,NOL3,BAK1,BBC3,BCL2,BCL2A1,BCL2L1,BCL2L10,BID,ERN1,KCNA3,MCL1,MOAP1,NOL3,PMAIP1,PPP1CA,SFN,SH3GLB1,SLC25A4,VDAC1,YWHAQ,GTF2B,MUC1,TAF1,TBP,TP53,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L10,BCL2L2,BNIPL,B

Protein Size: 218
Molecular Weight 24 kDa
Gene ID 581
NCBI Accession NM_004324, NP_004315
UniProt Q07812
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.