Complement Decay-Accelerating Factor (CD55) (Middle Region) Peptide
CD55
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CD55 products
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD55 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Synonyms
- CR Peptide, CROM Peptide, DAF Peptide, TC Peptide, Daf Peptide, Daf-GPI Peptide, Daf1 Peptide, GPI-DAF Peptide, CD55 molecule (Cromer blood group) Peptide, CD55 molecule, decay accelerating factor for complement Peptide, CD55 Peptide, Cd55 Peptide
- Background
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This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.
Alias Symbols: CR, CROM, DAF, TC
Protein Interaction Partner: CD14,CD55,CD97,CR1,FYN,GPLD1,LCK,CD55
Protein Size: 381 - Molecular Weight
- 41 kDa
- Gene ID
- 1604
- NCBI Accession
- NM_000574, NP_000565
- UniProt
- P08174
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